Details of the Target

General Information of Target

Target ID LDTP18086
Target Name Solute carrier family 35 member F5 (SLC35F5)
Gene Name SLC35F5
Gene ID 80255
Synonyms
NS5ATP3; Solute carrier family 35 member F5; Hepatitis C virus NS5A-transactivated protein 3; HCV NS5A-transactivated protein 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQPPVPGPLGLLDPAEGLSRRKKTSLWFVGSLLLVSVLIVTVGLAATTRTENVTVGGYYP
GIILGFGSFLGIIGINLVENRRQMLVAAIVFISFGVVAAFCCAIVDGVFAAQHIEPRPLT
TGRCQFYSSGVGYLYDVYQTEVTCHSLDGKCQLKVRSNTCYCCDLYACGSAEPSPAYYEF
IGVSGCQDVLHLYRLLWASAVLNVLGLFLGIITAAVLGAFKDMVPLSQLAYGPAVPPQTL
YNPAQQILAYAGFRLTPEPVPTCSSYPLPLQPCSRFPVAPSSALASSEDLQPPSPSSSGS
GLPGQAPPCYAPTYFPPGEKPPPYAP
Target Bioclass
Transporter and channel
Family
SLC35F solute transporter family
Subcellular location
Membrane
Function Putative solute transporter.
Uniprot ID
Q8WV83
Ensemble ID
ENST00000245680.7
HGNC ID
HGNC:23617

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL27 SNV: p.L215F .
HGC27 SNV: p.V396I .
SKOV3 SNV: p.G329C .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C492(0.79)  LDD1508  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HEK-293T C492(0.79)  LDD1508  [1]
 LDCM0226  AC11 HEK-293T C492(1.17)  LDD1509  [1]
 LDCM0277  AC18 HEK-293T C492(0.81)  LDD1516  [1]
 LDCM0278  AC19 HEK-293T C492(0.91)  LDD1517  [1]
 LDCM0279  AC2 HEK-293T C492(0.73)  LDD1518  [1]
 LDCM0284  AC24 HEK-293T C492(1.15)  LDD1523  [1]
 LDCM0286  AC26 HEK-293T C492(0.81)  LDD1525  [1]
 LDCM0287  AC27 HEK-293T C492(0.89)  LDD1526  [1]
 LDCM0290  AC3 HEK-293T C492(1.04)  LDD1529  [1]
 LDCM0293  AC32 HEK-293T C492(0.78)  LDD1532  [1]
 LDCM0295  AC34 HEK-293T C492(0.88)  LDD1534  [1]
 LDCM0296  AC35 HEK-293T C492(1.17)  LDD1535  [1]
 LDCM0302  AC40 HEK-293T C492(0.91)  LDD1541  [1]
 LDCM0304  AC42 HEK-293T C492(1.38)  LDD1543  [1]
 LDCM0305  AC43 HEK-293T C492(1.04)  LDD1544  [1]
 LDCM0310  AC48 HEK-293T C492(0.77)  LDD1549  [1]
 LDCM0313  AC50 HEK-293T C492(0.80)  LDD1552  [1]
 LDCM0314  AC51 HEK-293T C492(0.90)  LDD1553  [1]
 LDCM0319  AC56 HEK-293T C492(0.94)  LDD1558  [1]
 LDCM0321  AC58 HEK-293T C492(0.77)  LDD1560  [1]
 LDCM0322  AC59 HEK-293T C492(0.98)  LDD1561  [1]
 LDCM0328  AC64 HEK-293T C492(0.94)  LDD1567  [1]
 LDCM0345  AC8 HEK-293T C492(0.76)  LDD1569  [1]
 LDCM0275  AKOS034007705 HEK-293T C492(0.90)  LDD1514  [1]
 LDCM0371  CL102 HEK-293T C492(1.28)  LDD1575  [1]
 LDCM0375  CL106 HEK-293T C492(1.71)  LDD1579  [1]
 LDCM0380  CL110 HEK-293T C492(0.81)  LDD1584  [1]
 LDCM0384  CL114 HEK-293T C492(0.91)  LDD1588  [1]
 LDCM0388  CL118 HEK-293T C492(0.94)  LDD1592  [1]
 LDCM0390  CL12 HEK-293T C492(1.06)  LDD1594  [1]
 LDCM0393  CL122 HEK-293T C492(1.43)  LDD1597  [1]
 LDCM0397  CL126 HEK-293T C492(0.98)  LDD1601  [1]
 LDCM0401  CL14 HEK-293T C492(0.95)  LDD1605  [1]
 LDCM0405  CL18 HEK-293T C492(0.85)  LDD1609  [1]
 LDCM0406  CL19 HEK-293T C492(0.96)  LDD1610  [1]
 LDCM0407  CL2 HEK-293T C492(0.75)  LDD1611  [1]
 LDCM0412  CL24 HEK-293T C492(1.12)  LDD1616  [1]
 LDCM0414  CL26 HEK-293T C492(1.36)  LDD1618  [1]
 LDCM0419  CL30 HEK-293T C492(0.83)  LDD1623  [1]
 LDCM0420  CL31 HEK-293T C492(1.12)  LDD1624  [1]
 LDCM0425  CL36 HEK-293T C492(1.29)  LDD1629  [1]
 LDCM0432  CL42 HEK-293T C492(1.00)  LDD1636  [1]
 LDCM0433  CL43 HEK-293T C492(0.99)  LDD1637  [1]
 LDCM0438  CL48 HEK-293T C492(0.94)  LDD1642  [1]
 LDCM0441  CL50 HEK-293T C492(1.08)  LDD1645  [1]
 LDCM0445  CL54 HEK-293T C492(1.28)  LDD1648  [1]
 LDCM0446  CL55 HEK-293T C492(1.01)  LDD1649  [1]
 LDCM0451  CL6 HEK-293T C492(1.13)  LDD1654  [1]
 LDCM0452  CL60 HEK-293T C492(0.85)  LDD1655  [1]
 LDCM0454  CL62 HEK-293T C492(1.06)  LDD1657  [1]
 LDCM0458  CL66 HEK-293T C492(1.01)  LDD1661  [1]
 LDCM0459  CL67 HEK-293T C492(1.17)  LDD1662  [1]
 LDCM0462  CL7 HEK-293T C492(1.05)  LDD1665  [1]
 LDCM0465  CL72 HEK-293T C492(1.22)  LDD1668  [1]
 LDCM0467  CL74 HEK-293T C492(1.09)  LDD1670  [1]
 LDCM0471  CL78 HEK-293T C492(0.71)  LDD1674  [1]
 LDCM0472  CL79 HEK-293T C492(0.85)  LDD1675  [1]
 LDCM0478  CL84 HEK-293T C492(1.01)  LDD1681  [1]
 LDCM0480  CL86 HEK-293T C492(1.22)  LDD1683  [1]
 LDCM0485  CL90 HEK-293T C492(1.33)  LDD1688  [1]
 LDCM0486  CL91 HEK-293T C492(0.91)  LDD1689  [1]
 LDCM0491  CL96 HEK-293T C492(0.71)  LDD1694  [1]
 LDCM0493  CL98 HEK-293T C492(0.94)  LDD1696  [1]
 LDCM0427  Fragment51 HEK-293T C492(0.96)  LDD1631  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402