Details of the Target

General Information of Target

Target ID LDTP17298
Target Name Pecanex-like protein 4 (PCNX4)
Gene Name PCNX4
Gene ID 64430
Synonyms
C14orf135; FBP2; PCNXL4; Pecanex-like protein 4; Hepatitis C virus F protein-binding protein 2; HCV F protein-binding protein 2; Pecanex homolog protein 4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKEEDSSFKLCVPGIVALQSPPNKAFRSTDTVGFLESELKKLLGMQQESRLWKLGSQEGR
ELLTRPEITVVEGEGYEVQRRLRHLPSPISVAQCLLLEEKGEMGNWPPE
Target Bioclass
Other
Family
Pecanex family
Subcellular location
Membrane
Uniprot ID
Q63HM2
Ensemble ID
ENST00000406854.6
HGNC ID
HGNC:20349

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C947(0.87)  LDD1512  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0259  AC14 HEK-293T C947(0.87)  LDD1512  [1]
 LDCM0282  AC22 HEK-293T C947(0.86)  LDD1521  [1]
 LDCM0291  AC30 HEK-293T C947(0.85)  LDD1530  [1]
 LDCM0299  AC38 HEK-293T C947(0.86)  LDD1538  [1]
 LDCM0308  AC46 HEK-293T C947(0.93)  LDD1547  [1]
 LDCM0317  AC54 HEK-293T C947(1.02)  LDD1556  [1]
 LDCM0323  AC6 HEK-293T C947(1.03)  LDD1562  [1]
 LDCM0326  AC62 HEK-293T C947(1.01)  LDD1565  [1]
 LDCM0367  CL1 HEK-293T C947(0.87)  LDD1571  [1]
 LDCM0368  CL10 HEK-293T C947(1.03)  LDD1572  [1]
 LDCM0369  CL100 HEK-293T C947(0.81)  LDD1573  [1]
 LDCM0370  CL101 HEK-293T C947(1.15)  LDD1574  [1]
 LDCM0373  CL104 HEK-293T C947(0.98)  LDD1577  [1]
 LDCM0374  CL105 HEK-293T C947(0.85)  LDD1578  [1]
 LDCM0377  CL108 HEK-293T C947(1.10)  LDD1581  [1]
 LDCM0378  CL109 HEK-293T C947(0.83)  LDD1582  [1]
 LDCM0382  CL112 HEK-293T C947(1.08)  LDD1586  [1]
 LDCM0383  CL113 HEK-293T C947(1.06)  LDD1587  [1]
 LDCM0386  CL116 HEK-293T C947(0.69)  LDD1590  [1]
 LDCM0387  CL117 HEK-293T C947(1.02)  LDD1591  [1]
 LDCM0391  CL120 HEK-293T C947(0.76)  LDD1595  [1]
 LDCM0392  CL121 HEK-293T C947(1.13)  LDD1596  [1]
 LDCM0395  CL124 HEK-293T C947(0.96)  LDD1599  [1]
 LDCM0396  CL125 HEK-293T C947(1.03)  LDD1600  [1]
 LDCM0399  CL128 HEK-293T C947(1.22)  LDD1603  [1]
 LDCM0400  CL13 HEK-293T C947(1.14)  LDD1604  [1]
 LDCM0403  CL16 HEK-293T C947(0.96)  LDD1607  [1]
 LDCM0410  CL22 HEK-293T C947(0.85)  LDD1614  [1]
 LDCM0413  CL25 HEK-293T C947(1.01)  LDD1617  [1]
 LDCM0416  CL28 HEK-293T C947(0.80)  LDD1620  [1]
 LDCM0423  CL34 HEK-293T C947(0.92)  LDD1627  [1]
 LDCM0426  CL37 HEK-293T C947(0.97)  LDD1630  [1]
 LDCM0429  CL4 HEK-293T C947(1.01)  LDD1633  [1]
 LDCM0430  CL40 HEK-293T C947(0.88)  LDD1634  [1]
 LDCM0436  CL46 HEK-293T C947(0.86)  LDD1640  [1]
 LDCM0439  CL49 HEK-293T C947(1.10)  LDD1643  [1]
 LDCM0443  CL52 HEK-293T C947(0.88)  LDD1646  [1]
 LDCM0449  CL58 HEK-293T C947(0.93)  LDD1652  [1]
 LDCM0453  CL61 HEK-293T C947(1.00)  LDD1656  [1]
 LDCM0456  CL64 HEK-293T C947(1.05)  LDD1659  [1]
 LDCM0463  CL70 HEK-293T C947(0.96)  LDD1666  [1]
 LDCM0466  CL73 HEK-293T C947(0.93)  LDD1669  [1]
 LDCM0469  CL76 HEK-293T C947(1.10)  LDD1672  [1]
 LDCM0476  CL82 HEK-293T C947(0.87)  LDD1679  [1]
 LDCM0479  CL85 HEK-293T C947(1.39)  LDD1682  [1]
 LDCM0482  CL88 HEK-293T C947(0.95)  LDD1685  [1]
 LDCM0489  CL94 HEK-293T C947(0.99)  LDD1692  [1]
 LDCM0492  CL97 HEK-293T C947(0.83)  LDD1695  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402