Details of the Target

General Information of Target

Target ID LDTP16796
Target Name Zinc finger protein 749 (ZNF749)
Gene Name ZNF749
Gene ID 388567
Synonyms
Zinc finger protein 749
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MTTATRQEVLGLYRSIFRLARKWQATSGQMEDTIKEKQYILNEARTLFRKNKNLTDTDLI
KQCIDECTARIEIGLHYKIPYPRPIHLPPMGLTPLRGRGLRSQEKLRKLSKPVYLRSHDE
VS
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
O43361
Ensemble ID
ENST00000334181.5
HGNC ID
HGNC:32783

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C154(1.08)  LDD1507  [1]
IA-alkyne
 Probe Info  		C630(0.00); C651(0.00); C313(0.00); C153(0.00)  LDD0161  [2]
HHS-465
 Probe Info  		K610(0.00); K613(0.00); Y612(0.00)  LDD2240  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C154(1.08)  LDD1507  [1]
 LDCM0259  AC14 HEK-293T C154(0.96)  LDD1512  [1]
 LDCM0270  AC15 HEK-293T C154(0.96)  LDD1513  [1]
 LDCM0276  AC17 HEK-293T C154(1.04)  LDD1515  [1]
 LDCM0281  AC21 HEK-293T C154(0.90)  LDD1520  [1]
 LDCM0282  AC22 HEK-293T C154(0.82)  LDD1521  [1]
 LDCM0283  AC23 HEK-293T C154(1.10)  LDD1522  [1]
 LDCM0285  AC25 HEK-293T C154(0.98)  LDD1524  [1]
 LDCM0289  AC29 HEK-293T C154(0.98)  LDD1528  [1]
 LDCM0291  AC30 HEK-293T C154(0.93)  LDD1530  [1]
 LDCM0292  AC31 HEK-293T C154(1.02)  LDD1531  [1]
 LDCM0294  AC33 HEK-293T C154(1.13)  LDD1533  [1]
 LDCM0298  AC37 HEK-293T C154(0.86)  LDD1537  [1]
 LDCM0299  AC38 HEK-293T C154(0.94)  LDD1538  [1]
 LDCM0300  AC39 HEK-293T C154(0.99)  LDD1539  [1]
 LDCM0303  AC41 HEK-293T C154(1.30)  LDD1542  [1]
 LDCM0307  AC45 HEK-293T C154(1.11)  LDD1546  [1]
 LDCM0308  AC46 HEK-293T C154(0.92)  LDD1547  [1]
 LDCM0309  AC47 HEK-293T C154(1.10)  LDD1548  [1]
 LDCM0311  AC49 HEK-293T C154(1.21)  LDD1550  [1]
 LDCM0312  AC5 HEK-293T C154(0.78)  LDD1551  [1]
 LDCM0316  AC53 HEK-293T C154(1.03)  LDD1555  [1]
 LDCM0317  AC54 HEK-293T C154(0.98)  LDD1556  [1]
 LDCM0318  AC55 HEK-293T C154(1.00)  LDD1557  [1]
 LDCM0320  AC57 HEK-293T C154(1.12)  LDD1559  [1]
 LDCM0323  AC6 HEK-293T C154(0.99)  LDD1562  [1]
 LDCM0325  AC61 HEK-293T C154(1.13)  LDD1564  [1]
 LDCM0326  AC62 HEK-293T C154(0.95)  LDD1565  [1]
 LDCM0327  AC63 HEK-293T C154(0.88)  LDD1566  [1]
 LDCM0334  AC7 HEK-293T C154(0.88)  LDD1568  [1]
 LDCM0248  AKOS034007472 HEK-293T C154(1.12)  LDD1511  [1]
 LDCM0356  AKOS034007680 HEK-293T C154(1.01)  LDD1570  [1]
 LDCM0368  CL10 HEK-293T C154(1.29)  LDD1572  [1]
 LDCM0379  CL11 HEK-293T C154(0.93)  LDD1583  [1]
 LDCM0404  CL17 HEK-293T C154(1.23)  LDD1608  [1]
 LDCM0409  CL21 HEK-293T C154(1.22)  LDD1613  [1]
 LDCM0410  CL22 HEK-293T C154(0.98)  LDD1614  [1]
 LDCM0411  CL23 HEK-293T C154(1.01)  LDD1615  [1]
 LDCM0417  CL29 HEK-293T C154(1.07)  LDD1621  [1]
 LDCM0422  CL33 HEK-293T C154(1.06)  LDD1626  [1]
 LDCM0423  CL34 HEK-293T C154(1.00)  LDD1627  [1]
 LDCM0424  CL35 HEK-293T C154(1.06)  LDD1628  [1]
 LDCM0431  CL41 HEK-293T C154(1.23)  LDD1635  [1]
 LDCM0435  CL45 HEK-293T C154(1.10)  LDD1639  [1]
 LDCM0436  CL46 HEK-293T C154(1.10)  LDD1640  [1]
 LDCM0437  CL47 HEK-293T C154(1.09)  LDD1641  [1]
 LDCM0440  CL5 HEK-293T C154(1.08)  LDD1644  [1]
 LDCM0444  CL53 HEK-293T C154(1.13)  LDD1647  [1]
 LDCM0448  CL57 HEK-293T C154(1.07)  LDD1651  [1]
 LDCM0449  CL58 HEK-293T C154(0.96)  LDD1652  [1]
 LDCM0450  CL59 HEK-293T C154(0.99)  LDD1653  [1]
 LDCM0457  CL65 HEK-293T C154(0.94)  LDD1660  [1]
 LDCM0461  CL69 HEK-293T C154(0.90)  LDD1664  [1]
 LDCM0463  CL70 HEK-293T C154(0.98)  LDD1666  [1]
 LDCM0464  CL71 HEK-293T C154(1.08)  LDD1667  [1]
 LDCM0470  CL77 HEK-293T C154(1.04)  LDD1673  [1]
 LDCM0475  CL81 HEK-293T C154(1.07)  LDD1678  [1]
 LDCM0476  CL82 HEK-293T C154(0.91)  LDD1679  [1]
 LDCM0477  CL83 HEK-293T C154(1.06)  LDD1680  [1]
 LDCM0483  CL89 HEK-293T C154(1.07)  LDD1686  [1]
 LDCM0484  CL9 HEK-293T C154(0.83)  LDD1687  [1]
 LDCM0488  CL93 HEK-293T C154(1.20)  LDD1691  [1]
 LDCM0489  CL94 HEK-293T C154(0.90)  LDD1692  [1]
 LDCM0490  CL95 HEK-293T C154(1.06)  LDD1693  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010