Details of the Target

General Information of Target

Target ID LDTP16009
Target Name Uncharacterized protein C19orf44 (C19orf44)
Gene Name C19orf44
Gene ID 84167
Synonyms
Uncharacterized protein C19orf44
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MSAARPQFSIDDAFELSLEDGGPGPESSGVARFGPLHFERRARFEVADEDKQSRLRYQNL
ENDEDGAQASPEPDGGVGTRDSSRTSIRSSQWSFSTISSSTQRSYNTCCSWTQHPLIQKN
RRVVLASFLLLLLGLVLILVGVGLEATPSPGVSSAIFFVPGFLLLVPGVYHVIFIYCAVK
GHRGFQFFYLPYFEK
Target Bioclass
Other
Uniprot ID
Q9H6X5
Ensemble ID
ENST00000221671.8
HGNC ID
HGNC:26141

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
FTC133 SNV: p.L619M .
GB1 SNV: p.T479K .
HCT15 SNV: p.L650M .
KYSE30 SNV: p.A417V .
MCC13 SNV: p.P538L .
MFE296 Deletion: p.P299HfsTer28 .
MOLT4 Deletion: p.N233TfsTer26 .
WM793 SNV: p.S265R .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C79(0.99)  LDD1514  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0284  AC24 HEK-293T C79(1.07)  LDD1523  [1]
 LDCM0293  AC32 HEK-293T C79(0.92)  LDD1532  [1]
 LDCM0302  AC40 HEK-293T C79(1.00)  LDD1541  [1]
 LDCM0310  AC48 HEK-293T C79(1.03)  LDD1549  [1]
 LDCM0319  AC56 HEK-293T C79(1.02)  LDD1558  [1]
 LDCM0328  AC64 HEK-293T C79(0.88)  LDD1567  [1]
 LDCM0345  AC8 HEK-293T C79(0.93)  LDD1569  [1]
 LDCM0275  AKOS034007705 HEK-293T C79(0.99)  LDD1514  [1]
 LDCM0390  CL12 HEK-293T C79(1.06)  LDD1594  [1]
 LDCM0412  CL24 HEK-293T C79(1.18)  LDD1616  [1]
 LDCM0425  CL36 HEK-293T C79(1.06)  LDD1629  [1]
 LDCM0438  CL48 HEK-293T C79(0.95)  LDD1642  [1]
 LDCM0452  CL60 HEK-293T C79(1.16)  LDD1655  [1]
 LDCM0465  CL72 HEK-293T C79(1.11)  LDD1668  [1]
 LDCM0478  CL84 HEK-293T C79(1.03)  LDD1681  [1]
 LDCM0491  CL96 HEK-293T C79(1.01)  LDD1694  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402