Details of the Target

General Information of Target

Target ID LDTP15918
Target Name Small ribosomal subunit protein mS26 (MRPS26)
Gene Name MRPS26
Gene ID 64949
Synonyms
C20orf193; RPMS13; Small ribosomal subunit protein mS26; 28S ribosomal protein S13, mitochondrial; MRP-S13; S13mt; 28S ribosomal protein S26, mitochondrial; MRP-S26; S26mt
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLQFVRAGARAWLRPTGSQGLSSLAEEAARATENPEQVASEGLPEPVLRKVELPVPTHRR
PVQAWVESLRGFEQERVGLADLHPDVFATAPRLDILHQVAMWQKNFKRISYAKTKTRAEV
RGGGRKPWPQKGTGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTV
KLAQDDLHIMDSLELPTGDPQYLTELAHYRRWGDSVLLVDLTHEEMPQSIVEATSRLKTF
NLIPAVGLNVHSMLKHQTLVLTLPTVAFLEDKLLWQDSRYRPLYPFSLPYSDFPRPLPHA
TQGPAATPYHC
Target Bioclass
Other
Family
Mitochondrion-specific ribosomal protein mS26 family
Subcellular location
Mitochondrion
Uniprot ID
Q9BYN8
Ensemble ID
ENST00000380325.4
HGNC ID
HGNC:14045

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HPAP
 Probe Info  		3.52  LDD0062  [1]
IA-alkyne
 Probe Info  		C14(0.24)  LDD2182  [2]
Acrolein
 Probe Info  		N.A.  LDD0217  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0625  F8 Ramos C14(0.41)  LDD2187  [2]
 LDCM0572  Fragment10 Ramos C14(0.63)  LDD2189  [2]
 LDCM0573  Fragment11 Ramos C14(20.00)  LDD2190  [2]
 LDCM0574  Fragment12 Ramos C14(0.45)  LDD2191  [2]
 LDCM0575  Fragment13 Ramos C14(0.71)  LDD2192  [2]
 LDCM0576  Fragment14 Ramos C14(1.26)  LDD2193  [2]
 LDCM0579  Fragment20 Ramos C14(0.47)  LDD2194  [2]
 LDCM0580  Fragment21 Ramos C14(0.89)  LDD2195  [2]
 LDCM0582  Fragment23 Ramos C14(0.42)  LDD2196  [2]
 LDCM0578  Fragment27 Ramos C14(1.00)  LDD2197  [2]
 LDCM0588  Fragment30 Ramos C14(0.87)  LDD2199  [2]
 LDCM0589  Fragment31 Ramos C14(1.02)  LDD2200  [2]
 LDCM0590  Fragment32 Ramos C14(0.50)  LDD2201  [2]
 LDCM0468  Fragment33 Ramos C14(0.84)  LDD2202  [2]
 LDCM0566  Fragment4 Ramos C14(0.29)  LDD2184  [2]
 LDCM0610  Fragment52 Ramos C14(2.47)  LDD2204  [2]
 LDCM0614  Fragment56 Ramos C14(0.67)  LDD2205  [2]
 LDCM0569  Fragment7 Ramos C14(0.33)  LDD2186  [2]
 LDCM0571  Fragment9 Ramos C14(0.49)  LDD2188  [2]
 LDCM0022  KB02 Ramos C14(0.24)  LDD2182  [2]
 LDCM0023  KB03 Ramos C14(0.66)  LDD2183  [2]
 LDCM0024  KB05 Ramos C14(0.63)  LDD2185  [2]
 LDCM0014  Panhematin HEK-293T 3.52  LDD0062  [1]

References

1 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
2 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
3 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.