Details of the Target

General Information of Target

Target ID LDTP15829
Target Name Zinc finger protein 607 (ZNF607)
Gene Name ZNF607
Gene ID 84775
Synonyms
Zinc finger protein 607
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALTQGQVTFRDVAIEFSQEEWTCLDPAQRTLYRDVMLENYRNLASLGISCFDLSIISML
EQGKEPFTLESQVQIAGNPDGWEWIKAVITALSSEFVMKDLLHKGKSNTGEVFQTVMLER
QESQDIEGCSFREVQKNTHGLEYQCRDAEGNYKGVLLTQEGNLTHGRDEHDKRDARNKLI
KNQLGLSLQSHLPELQLFQYEGKIYECNQVEKSFNNNSSVSPPQQMPYNVKTHISKKYLK
DFISSLLLTQGQKANNWGSPYKSNGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRT
RSNLTTHQVIHTGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHL
VRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECGKVFTQNSHLTNHW
RIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKPYKCHECGKVFRRNSHLARHQLIHT
GEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLANHQRIHTGVKP
YMCNECGKAFSVYSSLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCN
ECGKVFRHNSYLSRHQRIHTGEKPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGK
VFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSV
RSSLTTHQAIHTGKKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKL
ARHQRIHTGEKPYECGKPFSICSSLTTHQTIHTGGKPYKCNVWKVLKSEFKPCKPSQNS
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q96SK3
Ensemble ID
ENST00000355202.9
HGNC ID
HGNC:28192

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
C4II SNV: p.Q351E .
CHL1 SNV: p.C566Y .
COLO320 SNV: p.E562K .
HCC1806 SNV: p.R96M .
HUH28 SNV: p.Q480E .
JURKAT SNV: p.G585S .
TOV21G SNV: p.A625V .
ZR751 SNV: p.H639Y .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C628(1.08)  LDD1514  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0284  AC24 HEK-293T C628(1.02)  LDD1523  [1]
 LDCM0293  AC32 HEK-293T C628(1.13)  LDD1532  [1]
 LDCM0302  AC40 HEK-293T C628(1.13)  LDD1541  [1]
 LDCM0310  AC48 HEK-293T C628(1.05)  LDD1549  [1]
 LDCM0319  AC56 HEK-293T C628(1.11)  LDD1558  [1]
 LDCM0328  AC64 HEK-293T C628(1.07)  LDD1567  [1]
 LDCM0345  AC8 HEK-293T C628(0.99)  LDD1569  [1]
 LDCM0275  AKOS034007705 HEK-293T C628(1.08)  LDD1514  [1]
 LDCM0390  CL12 HEK-293T C628(1.19)  LDD1594  [1]
 LDCM0412  CL24 HEK-293T C628(1.28)  LDD1616  [1]
 LDCM0425  CL36 HEK-293T C628(1.02)  LDD1629  [1]
 LDCM0438  CL48 HEK-293T C628(1.18)  LDD1642  [1]
 LDCM0452  CL60 HEK-293T C628(1.20)  LDD1655  [1]
 LDCM0465  CL72 HEK-293T C628(1.15)  LDD1668  [1]
 LDCM0478  CL84 HEK-293T C628(1.05)  LDD1681  [1]
 LDCM0491  CL96 HEK-293T C628(1.05)  LDD1694  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402