Details of the Target

General Information of Target

Target ID LDTP15086
Target Name Zinc finger protein 425 (ZNF425)
Gene Name ZNF425
Gene ID 155054
Synonyms
Zinc finger protein 425
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSPHLTALLGLVLCLAQTIHTQEGALPRPSISAEPGTVISPGSHVTFMCRGPVGVQTFRL
EREDRAKYKDSYNVFRLGPSESEARFHIDSVSEGNAGLYRCLYYKPPGWSEHSDFLELLV
KESSGGPDSPDTEPGSSAGTVPGTEASGFDAP
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function Acts as a transcriptional repressor.
Uniprot ID
Q6IV72
Ensemble ID
ENST00000378061.7
HGNC ID
HGNC:20690

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C315(1.05)  LDD1492  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0259  AC14 HEK-293T C279(1.07)  LDD1512  [1]
 LDCM0270  AC15 HEK-293T C279(1.05)  LDD1513  [1]
 LDCM0282  AC22 HEK-293T C279(1.00)  LDD1521  [1]
 LDCM0283  AC23 HEK-293T C279(0.98)  LDD1522  [1]
 LDCM0291  AC30 HEK-293T C279(0.94)  LDD1530  [1]
 LDCM0292  AC31 HEK-293T C279(1.04)  LDD1531  [1]
 LDCM0299  AC38 HEK-293T C279(1.43)  LDD1538  [1]
 LDCM0300  AC39 HEK-293T C279(0.98)  LDD1539  [1]
 LDCM0308  AC46 HEK-293T C279(1.04)  LDD1547  [1]
 LDCM0309  AC47 HEK-293T C279(1.03)  LDD1548  [1]
 LDCM0317  AC54 HEK-293T C279(1.05)  LDD1556  [1]
 LDCM0318  AC55 HEK-293T C279(0.96)  LDD1557  [1]
 LDCM0323  AC6 HEK-293T C279(1.13)  LDD1562  [1]
 LDCM0326  AC62 HEK-293T C279(1.12)  LDD1565  [1]
 LDCM0327  AC63 HEK-293T C279(1.02)  LDD1566  [1]
 LDCM0334  AC7 HEK-293T C279(0.95)  LDD1568  [1]
 LDCM0367  CL1 HEK-293T C279(1.04)  LDD1571  [1]
 LDCM0368  CL10 HEK-293T C279(0.93)  LDD1572  [1]
 LDCM0370  CL101 HEK-293T C279(0.95)  LDD1574  [1]
 LDCM0374  CL105 HEK-293T C279(0.94)  LDD1578  [1]
 LDCM0378  CL109 HEK-293T C279(0.93)  LDD1582  [1]
 LDCM0379  CL11 HEK-293T C279(1.03)  LDD1583  [1]
 LDCM0383  CL113 HEK-293T C279(1.04)  LDD1587  [1]
 LDCM0387  CL117 HEK-293T C279(0.94)  LDD1591  [1]
 LDCM0392  CL121 HEK-293T C279(1.06)  LDD1596  [1]
 LDCM0396  CL125 HEK-293T C279(1.01)  LDD1600  [1]
 LDCM0400  CL13 HEK-293T C279(0.96)  LDD1604  [1]
 LDCM0410  CL22 HEK-293T C279(1.01)  LDD1614  [1]
 LDCM0411  CL23 HEK-293T C279(1.11)  LDD1615  [1]
 LDCM0413  CL25 HEK-293T C279(0.92)  LDD1617  [1]
 LDCM0423  CL34 HEK-293T C279(1.04)  LDD1627  [1]
 LDCM0424  CL35 HEK-293T C279(1.05)  LDD1628  [1]
 LDCM0426  CL37 HEK-293T C279(0.94)  LDD1630  [1]
 LDCM0436  CL46 HEK-293T C279(1.07)  LDD1640  [1]
 LDCM0437  CL47 HEK-293T C279(0.99)  LDD1641  [1]
 LDCM0439  CL49 HEK-293T C279(0.93)  LDD1643  [1]
 LDCM0449  CL58 HEK-293T C279(0.87)  LDD1652  [1]
 LDCM0450  CL59 HEK-293T C279(1.06)  LDD1653  [1]
 LDCM0453  CL61 HEK-293T C279(1.08)  LDD1656  [1]
 LDCM0463  CL70 HEK-293T C279(1.06)  LDD1666  [1]
 LDCM0464  CL71 HEK-293T C279(0.99)  LDD1667  [1]
 LDCM0466  CL73 HEK-293T C279(0.96)  LDD1669  [1]
 LDCM0476  CL82 HEK-293T C279(1.36)  LDD1679  [1]
 LDCM0477  CL83 HEK-293T C279(1.01)  LDD1680  [1]
 LDCM0479  CL85 HEK-293T C279(0.96)  LDD1682  [1]
 LDCM0489  CL94 HEK-293T C279(1.04)  LDD1692  [1]
 LDCM0490  CL95 HEK-293T C279(1.02)  LDD1693  [1]
 LDCM0492  CL97 HEK-293T C279(1.11)  LDD1695  [1]
 LDCM0022  KB02 HEK-293T C315(1.05)  LDD1492  [1]
 LDCM0023  KB03 HEK-293T C315(1.17)  LDD1497  [1]
 LDCM0024  KB05 HEK-293T C315(1.02)  LDD1502  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402