Details of the Target

General Information of Target

Target ID LDTP10485
Target Name PiggyBac transposable element-derived protein 1 (PGBD1)
Gene Name PGBD1
Gene ID 84547
Synonyms
PiggyBac transposable element-derived protein 1; Cerebral protein 4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLK
GEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIA
AGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSI
LMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
Target Bioclass
Other
Uniprot ID
Q96JS3
Ensemble ID
ENST00000259883.3
HGNC ID
HGNC:19398

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C384(3.90)  LDD3340  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0237  AC12 HEK-293T C625(0.88)  LDD1510  [2]
 LDCM0270  AC15 HEK-293T C625(1.06)  LDD1513  [2]
 LDCM0280  AC20 HEK-293T C625(0.92)  LDD1519  [2]
 LDCM0283  AC23 HEK-293T C625(1.02)  LDD1522  [2]
 LDCM0288  AC28 HEK-293T C625(0.74)  LDD1527  [2]
 LDCM0292  AC31 HEK-293T C625(0.83)  LDD1531  [2]
 LDCM0297  AC36 HEK-293T C625(0.89)  LDD1536  [2]
 LDCM0300  AC39 HEK-293T C625(0.92)  LDD1539  [2]
 LDCM0301  AC4 HEK-293T C625(0.97)  LDD1540  [2]
 LDCM0306  AC44 HEK-293T C625(1.22)  LDD1545  [2]
 LDCM0309  AC47 HEK-293T C625(0.86)  LDD1548  [2]
 LDCM0315  AC52 HEK-293T C625(0.86)  LDD1554  [2]
 LDCM0318  AC55 HEK-293T C625(0.85)  LDD1557  [2]
 LDCM0324  AC60 HEK-293T C625(0.99)  LDD1563  [2]
 LDCM0327  AC63 HEK-293T C625(0.87)  LDD1566  [2]
 LDCM0334  AC7 HEK-293T C625(1.15)  LDD1568  [2]
 LDCM0379  CL11 HEK-293T C625(0.74)  LDD1583  [2]
 LDCM0408  CL20 HEK-293T C625(0.60)  LDD1612  [2]
 LDCM0411  CL23 HEK-293T C625(0.70)  LDD1615  [2]
 LDCM0421  CL32 HEK-293T C625(0.92)  LDD1625  [2]
 LDCM0424  CL35 HEK-293T C625(0.73)  LDD1628  [2]
 LDCM0434  CL44 HEK-293T C625(0.70)  LDD1638  [2]
 LDCM0437  CL47 HEK-293T C625(0.97)  LDD1641  [2]
 LDCM0447  CL56 HEK-293T C625(1.10)  LDD1650  [2]
 LDCM0450  CL59 HEK-293T C625(0.90)  LDD1653  [2]
 LDCM0460  CL68 HEK-293T C625(0.96)  LDD1663  [2]
 LDCM0464  CL71 HEK-293T C625(0.76)  LDD1667  [2]
 LDCM0473  CL8 HEK-293T C625(0.39)  LDD1676  [2]
 LDCM0474  CL80 HEK-293T C625(1.12)  LDD1677  [2]
 LDCM0477  CL83 HEK-293T C625(0.80)  LDD1680  [2]
 LDCM0487  CL92 HEK-293T C625(0.80)  LDD1690  [2]
 LDCM0490  CL95 HEK-293T C625(0.64)  LDD1693  [2]
 LDCM0022  KB02 Kelly C384(2.31)  LDD2417  [1]
 LDCM0023  KB03 Kelly C384(2.97)  LDD2834  [1]
 LDCM0024  KB05 NB1 C384(3.90)  LDD3340  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402