Details of the Target

General Information of Target

Target ID LDTP10380
Target Name Protein N-terminal glutamine amidohydrolase (NTAQ1)
Gene Name NTAQ1
Gene ID 55093
Synonyms
C8orf32; WDYHV1; Protein N-terminal glutamine amidohydrolase; EC 3.5.1.122; Protein NH2-terminal glutamine deamidase; N-terminal Gln amidase; Nt(Q)-amidase; WDYHV motif-containing protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSLERELRQLSKAKAKAQRAGQRREEAALCHQLGELLAGHGRYAEALEQHWQELQLRERA
DDPLGCAVAHRKIGERLAEMEDYPAALQHQHQYLELAHSLRNHTELQRAWATIGRTHLDI
YDHCQSRDALLQAQAAFEKSLAIVDEELEGTLAQGELNEMRTRLYLNLGLTFESLQQTAL
CNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKRFM
ESECCVVIAQVLQDLGDFLAAKRALKKAYRLGSQKPVQRAAICQNLQHVLAVVRLQQQLE
EAEGRDPQGAMVICEQLGDLFSKAGDFPRAAEAYQKQLRFAELLDRPGAERAIIHVSLAT
TLGDMKDHHGAVRHYEEELRLRSGNVLEEAKTWLNIALSREEAGDAYELLAPCFQKALSC
AQQAQRPQLQRQVLQHLHTVQLRLQPQEAPETETRLRELSVAEDEDEEEEAEEAAATAES
EALEAGEVELSEGEDDTDGLTPQLEEDEELQGHLGRRKGSKWNRRNDMGETLLHRACIEG
QLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAVDDPGGQGCEGIT
PLHDALNCGHFEVAELLLERGASVTLRTRKGLSPLETLQQWVKLYRRDLDLETRQKARAM
EMLLQAAASGQDPHSSQAFHTPSSLLFDPETSPPLSPCPEPPSNSTRLPEASQAHVRVSP
GQAAPAMARPRRSRHGPASSSSSSEGEDSAGPARPSQKRPRCSATAQRVAAWTPGPASNR
EAATASTSRAAYQAAIRGVGSAQSRLGPGPPRGHSKALAPQAALIPEEECLAGDWLELDM
PLTRSRRPRPRGTGDNRRPSSTSGSDSEESRPRARAKQVRLTCMQSCSAPVNAGPSSLAS
EPPGSPSTPRVSEPSGDSSAAGQPLGPAPPPPIRVRVQVQDHLFLIPVPHSSDTHSVAWL
AEQAAQRYYQTCGLLPRLTLRKEGALLAPQDLIPDVLQSNDEVLAEVTSWDLPPLTDRYR
RACQSLGQGEHQQVLQAVELQGLGLSFSACSLALDQAQLTPLLRALKLHTALRELRLAGN
RLGDKCVAELVAALGTMPSLALLDLSSNHLGPEGLRQLAMGLPGQATLQSLEELDLSMNP
LGDGCGQSLASLLHACPLLSTLRLQACGFGPSFFLSHQTALGSAFQDAEHLKTLSLSYNA
LGAPALARTLQSLPAGTLLHLELSSVAAGKGDSDLMEPVFRYLAKEGCALAHLTLSANHL
GDKAVRDLCRCLSLCPSLISLDLSANPEISCASLEELLSTLQKRPQGLSFLGLSGCAVQG
PLGLGLWDKIAAQLRELQLCSRRLCAEDRDALRQLQPSRPGPGECTLDHGSKLFFRRL
Target Bioclass
Enzyme
Family
NTAQ1 family
Subcellular location
Cytoplasm, cytosol
Function
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Uniprot ID
Q96HA8
Ensemble ID
ENST00000287387.7
HGNC ID
HGNC:25490

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAMA1 SNV: p.R131T .
IGR1 SNV: p.P17T .
Ishikawa (Heraklio) 02 ER SNV: p.S15T .
NCIH1155 SNV: p.F54L .
RL952 SNV: p.N174S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C28(0.79)  LDD0593  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0276  AC17 HCT 116 C28(0.79)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C28(1.48)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C28(1.03)  LDD0595  [1]
 LDCM0280  AC20 HCT 116 C28(1.54)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C28(1.05)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C28(1.36)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C28(1.03)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C28(1.68)  LDD0601  [1]
 LDCM0308  AC46 HCT 116 C28(1.28)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C28(0.76)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C28(1.12)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C28(3.11)  LDD0628  [1]
 LDCM0313  AC50 HCT 116 C28(1.57)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C28(1.97)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C28(1.54)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C28(1.13)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C28(1.25)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C28(0.84)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C28(1.66)  LDD0636  [1]
 LDCM0332  AC68 HCT 116 C28(1.41)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C28(0.83)  LDD0650  [1]
 LDCM0335  AC70 HCT 116 C28(1.22)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C28(0.93)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C28(1.15)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C28(1.13)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C28(0.98)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C28(1.01)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C28(0.88)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C28(1.14)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C28(0.89)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C28(1.35)  LDD0661  [1]
 LDCM0346  AC80 HCT 116 C28(0.77)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C28(0.99)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C28(1.48)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C28(0.13)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C28(0.12)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C28(0.12)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C28(0.10)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C28(0.10)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C28(0.12)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C28(0.11)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C28(0.13)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C28(0.08)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C28(0.09)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C28(0.13)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C28(0.08)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C28(0.12)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C28(0.11)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C28(0.10)  LDD0681  [1]
 LDCM0374  CL105 HCT 116 C28(0.69)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C28(0.68)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C28(0.68)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C28(0.67)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C28(1.46)  LDD0695  [1]
 LDCM0380  CL110 HCT 116 C28(0.90)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C28(0.98)  LDD0698  [1]
 LDCM0392  CL121 HCT 116 C28(1.05)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C28(1.42)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C28(1.23)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C28(0.98)  LDD0712  [1]
 LDCM0436  CL46 HCT 116 C28(0.88)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C28(0.97)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C28(0.67)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C28(0.61)  LDD0756  [1]
 LDCM0441  CL50 HCT 116 C28(0.66)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C28(0.79)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C28(0.81)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C28(2.18)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C28(0.77)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C28(0.70)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C28(0.89)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C28(1.00)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C28(0.73)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C28(0.76)  LDD0767  [1]
 LDCM0452  CL60 HCT 116 C28(0.83)  LDD0769  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 81 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytosolic 5'-nucleotidase 1A (NT5C1A) 5'-nucleotidase type 3 family Q9BXI3
Transitional endoplasmic reticulum ATPase (VCP) AAA ATPase family P55072
Pachytene checkpoint protein 2 homolog (TRIP13) AAA ATPase family Q15645
Diamine acetyltransferase 1 (SAT1) Acetyltransferase family P21673
Actin, cytoplasmic 1 (ACTB) Actin family P60709
Actin, cytoplasmic 2 (ACTG1) Actin family P63261
Anterior gradient protein 2 homolog (AGR2) AGR family O95994
Anterior gradient protein 3 (AGR3) AGR family Q8TD06
Methylthioribulose-1-phosphate dehydratase (APIP) Aldolase class II family Q96GX9
DNA-directed RNA polymerase II subunit RPB11-a (POLR2J) Archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family P52435
Casein kinase II subunit beta (CSNK2B) Casein kinase 2 subunit beta family P67870
Glycine N-methyltransferase (GNMT) Glycine N-methyltransferase family Q14749
Protein arginine N-methyltransferase 1 (PRMT1) Protein arginine N-methyltransferase family Q99873
Protein arginine N-methyltransferase 5 (PRMT5) Protein arginine N-methyltransferase family O14744
Serine--tRNA ligase, mitochondrial (SARS2) Class-II aminoacyl-tRNA synthetase family Q9NP81
Diamine oxidase [copper-containing] (AOC1) Copper/topaquinone oxidase family P19801
Cytidine deaminase (CDA) Cytidine and deoxycytidylate deaminase family P32320
N-acetylneuraminate lyase (NPL) DapA family Q9BXD5
Deoxyhypusine synthase (DHPS) Deoxyhypusine synthase family P49366
Glutathione peroxidase 7 (GPX7) Glutathione peroxidase family Q96SL4
Glycogen phosphorylase, muscle form (PYGM) Glycogen phosphorylase family P11217
Glutathione S-transferase A4 (GSTA4) Alpha family O15217
Glutathione S-transferase omega-2 (GSTO2) Omega family Q9H4Y5
Phosphopantothenoylcysteine decarboxylase (PPCDC) HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily Q96CD2
Homogentisate 1,2-dioxygenase (HGD) Homogentisate dioxygenase family Q93099
Baculoviral IAP repeat-containing protein 2 (BIRC2) IAP family Q13490
Baculoviral IAP repeat-containing protein 7 (BIRC7) IAP family Q96CA5
E3 ubiquitin-protein ligase XIAP (XIAP) IAP family P98170
Argininosuccinate lyase (ASL) Lyase 1 family P04424
Protein mab-21-like 3 (MAB21L3) Mab-21 family Q8N8X9
Macrophage migration inhibitory factor (MIF) MIF family P14174
Glutamine-dependent NAD(+) synthetase (NADSYN1) NAD synthetase family Q6IA69
GDP-mannose 4,6 dehydratase (GMDS) NAD(P)-dependent epimerase/dehydratase family O60547
Nucleoside diphosphate kinase A (NME1) NDK family P15531
Uridine diphosphate glucose pyrophosphatase NUDT14 (NUDT14) Nudix hydrolase family O95848
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) Nudix hydrolase family O43809
Tudor-interacting repair regulator protein (NUDT16L1) Nudix hydrolase family Q9BRJ7
Bleomycin hydrolase (BLMH) Peptidase C1 family Q13867
Caspase-6 (CASP6) Peptidase C14A family P55212
Calpain-3 (CAPN3) Peptidase C2 family P20807
Aminoacylase-1 (ACY1) Peptidase M20A family Q03154
Proteasome subunit beta type-5 (PSMB5) Peptidase T1B family P28074
Group 10 secretory phospholipase A2 (PLA2G10) Phospholipase A2 family O15496
Protein phosphatase Mn(2+)-dependent 1K (PPM1K) PP2C family Q8N3J5
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2A) CAMK Ser/Thr protein kinase family Q9UQM7
Serine/threonine-protein kinase PAK 5 (PAK5) STE Ser/Thr protein kinase family Q9P286
Pterin-4-alpha-carbinolamine dehydratase (PCBD1) Pterin-4-alpha-carbinolamine dehydratase family P61457
6-pyruvoyl tetrahydrobiopterin synthase (PTS) PTPS family Q03393
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) Purine/pyrimidine phosphoribosyltransferase family P00492
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) Purine/pyrimidine phosphoribosyltransferase family Q9NRG1
Pyrroline-5-carboxylate reductase 3 (PYCR3) Pyrroline-5-carboxylate reductase family Q53H96
Ribose-5-phosphate isomerase (RPIA) Ribose 5-phosphate isomerase family P49247
Ribose-phosphate pyrophosphokinase 2 (PRPS2) Ribose-phosphate pyrophosphokinase family P11908
Exosome complex component RRP43 (EXOSC8) RNase PH family Q96B26
17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14) Short-chain dehydrogenases/reductases (SDR) family Q9BPX1
E3 ubiquitin-protein ligase SIAH1 (SIAH1) SINA (Seven in absentia) family Q8IUQ4
E3 ubiquitin-protein ligase TRIM23 (TRIM23) Arf family P36406
Rho-related GTP-binding protein RhoQ (RHOQ) Rho family P17081
DNA repair and recombination protein RAD54-like (RAD54L) SNF2/RAD54 helicase family Q92698
Acyl-coenzyme A thioesterase 13 (ACOT13) Thioesterase PaaI family Q9NPJ3
TNF receptor-associated factor 3 (TRAF3) TNF receptor-associated factor family Q13114
Neuronal-specific septin-3 (SEPTIN3) Septin GTPase family Q9UH03
Septin-14 (SEPTIN14) Septin GTPase family Q6ZU15
Cystathionine gamma-lyase (CTH) Trans-sulfuration enzymes family P32929
Translin (TSN) Translin family Q15631
E3 ubiquitin-protein ligase TRIM32 (TRIM32) TRIM/RBCC family Q13049
E3 ubiquitin-protein ligase TRIM9 (TRIM9) TRIM/RBCC family Q9C026
Zinc finger protein RFP (TRIM27) TRIM/RBCC family P14373
Probable tRNA(His) guanylyltransferase (THG1L) TRNA(His) guanylyltransferase family Q9NWX6
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (PLCD1) . P51178
BTB/POZ domain-containing protein 1 (BTBD1) . Q9H0C5
BTB/POZ domain-containing protein 2 (BTBD2) . Q9BX70
dCTP pyrophosphatase 1 (DCTPP1) . Q9H773
E3 SUMO-protein ligase ZBED1 (ZBED1) . O96006
E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1) . Q9NPC3
E3 ubiquitin-protein ligase RNF138 (RNF138) . Q8WVD3
E3 ubiquitin-protein ligase RNF4 (RNF4) . P78317
LON peptidase N-terminal domain and RING finger protein 1 (LONRF1) . Q17RB8
Probable E3 ubiquitin-protein ligase MARCHF10 (MARCHF10) . Q8NA82
Prolyl hydroxylase EGLN3 (EGLN3) . Q9H6Z9
Tripartite motif-containing protein 54 (TRIM54) . Q9BYV2
Transporter and channel
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Alpha-actinin-2 (ACTN2) Alpha-actinin family P35609
Copper homeostasis protein cutC homolog (CUTC) CutC family Q9NTM9
Leucine zipper putative tumor suppressor 1 (LZTS1) LZTS family Q9Y250
Solute carrier family 15 member 2 (SLC15A2) Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family Q16348
Potassium voltage-gated channel subfamily H member 1 (KCNH1) Potassium channel family O95259
Prenylated Rab acceptor protein 1 (RABAC1) PRA1 family Q9UI14
Histone deacetylase complex subunit SAP18 (SAP18) SAP18 family O00422
Alpha-crystallin A chain (CRYAA) Small heat shock protein (HSP20) family P02489
V-type proton ATPase subunit G 1 (ATP6V1G1) V-ATPase G subunit family O75348
AP-4 complex accessory subunit Tepsin (TEPSIN) . Q96N21
Kelch-like protein 2 (KLHL2) . O95198
Major vault protein (MVP) . Q14764
TIR domain-containing adapter molecule 2 (TICAM2) . Q86XR7
Transcription factor
Click To Hide/Show 19 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-B6 (HOXB6) Antp homeobox family P17509
Transcription factor ETV6 (ETV6) ETS family P41212
Zinc finger and SCAN domain-containing protein 16 (ZSCAN16) Krueppel C2H2-type zinc-finger protein family Q9H4T2
Zinc finger protein 165 (ZNF165) Krueppel C2H2-type zinc-finger protein family P49910
Zinc finger protein 341 (ZNF341) Krueppel C2H2-type zinc-finger protein family Q9BYN7
Zinc finger protein 436 (ZNF436) Krueppel C2H2-type zinc-finger protein family Q9C0F3
Zinc finger protein 511 (ZNF511) Krueppel C2H2-type zinc-finger protein family Q8NB15
Zinc finger protein 618 (ZNF618) Krueppel C2H2-type zinc-finger protein family Q5T7W0
Leucine zipper transcription factor-like protein 1 (LZTFL1) LZTFL1 family Q9NQ48
Steroidogenic factor 1 (NR5A1) Nuclear hormone receptor family Q13285
THAP domain-containing protein 1 (THAP1) THAP1 family Q9NVV9
TSC22 domain family protein 1 (TSC22D1) TSC-22/Dip/Bun family Q15714
Golgin-45 (BLZF1) . Q9H2G9
High mobility group protein 20A (HMG20A) . Q9NP66
T-box transcription factor TBX15 (TBX15) . Q96SF7
THAP domain-containing protein 6 (THAP6) . Q8TBB0
THAP domain-containing protein 7 (THAP7) . Q9BT49
Zinc finger and BTB domain-containing protein 8A (ZBTB8A) . Q96BR9
Zinc finger and BTB domain-containing protein 8B (ZBTB8B) . Q8NAP8
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Matrix remodeling-associated protein 8 (MXRA8) . Q9BRK3
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Interleukin-31 (IL31) . Q6EBC2
Other
Click To Hide/Show 177 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
14-3-3 protein sigma (SFN) 14-3-3 family P31947
Acyl carrier protein, mitochondrial (NDUFAB1) Acyl carrier protein (ACP) family O14561
Akirin-2 (AKIRIN2) Akirin family Q53H80
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) ARL6ip family Q15041
Large ribosomal subunit protein bL12m (MRPL12) Bacterial ribosomal protein bL12 family P52815
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (KCTD13) BACURD family Q8WZ19
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1) BACURD family Q13829
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (KCTD10) BACURD family Q9H3F6
Junction plakoglobin (JUP) Beta-catenin family P14923
BLOC-1-related complex subunit 6 (BORCS6) BORCS6 family Q96GS4
Borealin (CDCA8) Borealin family Q53HL2
BPI fold-containing family B member 3 (BPIFB3) BPI/LBP family P59826
cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) CAMP-dependent kinase regulatory chain family P31321
CDKN2AIP N-terminal-like protein (CDKN2AIPNL) CARF family Q96HQ2
Caveolae-associated protein 4 (CAVIN4) CAVIN family Q5BKX8
Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) CDK2AP family O14519
Cerebellar degeneration-related protein 2 (CDR2) CDR2 family Q01850
Centromere protein P (CENPP) CENP-P/CTF19 family Q6IPU0
Deuterosome assembly protein 1 (DEUP1) CEP63 family Q05D60
Conserved oligomeric Golgi complex subunit 6 (COG6) COG6 family Q9Y2V7
Coilin (COIL) Coilin family P38432
Cancer/testis antigen family 45 member A1 (CT45A1) CT45 family Q5HYN5
Cancer/testis antigen 1 (CTAG1A; CTAG1B) CTAG/PCC1 family P78358
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Dynein axonemal light chain 4 (DNAL4) Dynein light chain family O96015
Dynein light chain Tctex-type 1 (DYNLT1) Dynein light chain Tctex-type family P63172
Translation initiation factor eIF2B subunit alpha (EIF2B1) EIF-2B alpha/beta/delta subunits family Q14232
Endophilin-B2 (SH3GLB2) Endophilin family Q9NR46
Protein FAM136A (FAM136A) FAM136 family Q96C01
Protein FAM72A (FAM72A) FAM72 family Q5TYM5
Protein FAM72D (FAM72D) FAM72 family Q6L9T8
Ferritin light chain (FTL) Ferritin family P02792
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (FKBP6) FKBP6 family O75344
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 (GNG3) G protein gamma family P63215
Hemoglobin subunit theta-1 (HBQ1) Globin family P09105
Hemoglobin subunit zeta (HBZ) Globin family P02008
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1
10 kDa heat shock protein, mitochondrial (HSPE1) GroES chaperonin family P61604
General transcription factor IIH subunit 2-like protein (GTF2H2C; GTF2H2C_2) GTF2H2 family Q6P1K8
HAUS augmin-like complex subunit 8 (HAUS8) HAUS8 family Q9BT25
Iron-sulfur cluster assembly 2 homolog, mitochondrial (ISCA2) HesB/IscA family Q86U28
Homer protein homolog 3 (HOMER3) Homer family Q9NSC5
Checkpoint protein HUS1 (HUS1) HUS1 family O60921
Protein INCA1 (INCA1) INCA family Q0VD86
Glial fibrillary acidic protein (GFAP) Intermediate filament family P14136
Keratin, type I cuticular Ha1 (KRT31) Intermediate filament family Q15323
Keratin, type I cytoskeletal 27 (KRT27) Intermediate filament family Q7Z3Y8
Mitochondrial assembly of ribosomal large subunit protein 1 (MALSU1) Iojap/RsfS family Q96EH3
Kelch-like ECH-associated protein 1 (KEAP1) KEAP1 family Q14145
Oocyte-expressed protein homolog (OOEP) KHDC1 family A6NGQ2
Keratin-associated protein 10-5 (KRTAP10-5) KRTAP type 10 family P60370
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Keratin-associated protein 19-2 (KRTAP19-2) KRTAP type 19 family Q3LHN2
Keratin-associated protein 19-6 (KRTAP19-6) KRTAP type 19 family Q3LI70
Keratin-associated protein 3-1 (KRTAP3-1) KRTAP type 3 family Q9BYR8
Keratin-associated protein 3-3 (KRTAP3-3) KRTAP type 3 family Q9BYR6
Keratin-associated protein 4-2 (KRTAP4-2) KRTAP type 4 family Q9BYR5
Keratin-associated protein 5-9 (KRTAP5-9) KRTAP type 5 family P26371
Keratin-associated protein 6-1 (KRTAP6-1) KRTAP type 6 family Q3LI64
Keratin-associated protein 9-2 (KRTAP9-2) KRTAP type 9 family Q9BYQ4
Keratin-associated protein 9-4 (KRTAP9-4) KRTAP type 9 family Q9BYQ2
Keratin-associated protein 9-8 (KRTAP9-8) KRTAP type 9 family Q9BYQ0
Late cornified envelope protein 1C (LCE1C) LCE family Q5T751
Late cornified envelope protein 1D (LCE1D) LCE family Q5T752
Late cornified envelope protein 1E (LCE1E) LCE family Q5T753
Late cornified envelope protein 1F (LCE1F) LCE family Q5T754
Late cornified envelope protein 2C (LCE2C) LCE family Q5TA81
Late cornified envelope protein 5A (LCE5A) LCE family Q5TCM9
LIM domain-binding protein 2 (LDB2) LDB family O43679
Protein lin-7 homolog B (LIN7B) Lin-7 family Q9HAP6
Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) LRIF1 family Q5T3J3
Protein LSM12 (LSM12) LSM12 family Q3MHD2
Leucine zipper putative tumor suppressor 2 (LZTS2) LZTS2 family Q9BRK4
Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1) MAD1 family Q9Y6D9
MICOS complex subunit MIC19 (CHCHD3) MICOS complex subunit Mic19 family Q9NX63
Protein Mis18-alpha (MIS18A) Mis18 family Q9NYP9
Large ribosomal subunit protein mL64 (GADD45GIP1) Mitochondrion-specific ribosomal protein mL64 family Q8TAE8
MOB kinase activator 2 (MOB2) MOB1/phocein family Q70IA6
MORF4 family-associated protein 1-like 1 (MRFAP1L1) MORF4 family-associated protein family Q96HT8
Microtubule-associated tumor suppressor candidate 2 (MTUS2) MTUS1 family Q5JR59
NEDD4-binding protein 3 (N4BP3) N4BP3 family O15049
NGFI-A-binding protein 2 (NAB2) NAB family Q15742
Proteasome activator complex subunit 3 (PSME3) PA28 family P61289
PIH1 domain-containing protein 2 (PIH1D2) PIH1 family Q8WWB5
Paraneoplastic antigen Ma1 (PNMA1) PNMA family Q8ND90
Paraneoplastic antigen Ma2 (PNMA2) PNMA family Q9UL42
Paraneoplastic antigen-like protein 5 (PNMA5) PNMA family Q96PV4
Pro-opiomelanocortin (POMC) POMC family P01189
Prefoldin subunit 5 (PFDN5) Prefoldin subunit alpha family Q99471
Proline-rich protein 20D (PRR20D) PRR20 family P86480
Proline-rich protein 23B (PRR23B) PRR23 family Q6ZRT6
RNA-binding protein 48 (RBM48) RBM48 family Q5RL73
Ropporin-1A (ROPN1) Ropporin family Q9HAT0
Protein S100-A11 (S100A11) S-100 family P31949
Selenoprotein V (SELENOV) SelWTH family P59797
Suppressor of IKBKE 1 (SIKE1) SIKE family Q9BRV8
SLAIN motif-containing protein 1 (SLAIN1) SLAIN motif-containing family Q8ND83
Synaptosomal-associated protein 29 (SNAP29) SNAP-25 family O95721
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) SnRNP core protein family P62318
Sperm protein associated with the nucleus on the X chromosome B1 (SPANXB1) SPAN-X family Q9NS25
Speedy protein E4 (SPDYE4) Speedy/Ringo family A6NLX3
Microtubule nucleation factor SSNA1 (SSNA1) SSNA1 family O43805
Stathmin-2 (STMN2) Stathmin family Q93045
CST complex subunit STN1 (STN1) STN1 family Q9H668
Syntaxin-11 (STX11) Syntaxin family O75558
T-cell leukemia/lymphoma protein 1A (TCL1A) TCL1 family P56279
T-complex protein 10A homolog 1 (TCP10L) TCP10 family Q8TDR4
Tektin-1 (TEKT1) Tektin family Q969V4
TRAF-interacting protein with FHA domain-containing protein A (TIFA) TIFA family Q96CG3
TNF receptor-associated factor 5 (TRAF5) TNF receptor-associated factor family O00463
Toll-interacting protein (TOLLIP) Tollip family Q9H0E2
Translin-associated protein X (TSNAX) Translin family Q99598
Ubiquitin-fold modifier-conjugating enzyme 1 (UFC1) Ubiquitin-conjugating enzyme family Q9Y3C8
Protein VAC14 homolog (VAC14) VAC14 family Q08AM6
Vexin (VXN) Vexin family Q8TAG6
Vacuolar protein sorting-associated protein 37C (VPS37C) VPS37 family A5D8V6
Alanine and arginine-rich domain-containing protein (AARD) . Q4LEZ3
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) . Q13155
Antileukoproteinase (SLPI) . P03973
AP-4 complex accessory subunit RUSC1 (RUSC1) . Q9BVN2
BEN domain-containing protein 5 (BEND5) . Q7L4P6
BTB/POZ domain-containing protein KCTD1 (KCTD1) . Q719H9
BTB/POZ domain-containing protein KCTD21 (KCTD21) . Q4G0X4
BTB/POZ domain-containing protein KCTD4 (KCTD4) . Q8WVF5
BTB/POZ domain-containing protein KCTD6 (KCTD6) . Q8NC69
BTB/POZ domain-containing protein KCTD9 (KCTD9) . Q7L273
Centromere protein R (ITGB3BP) . Q13352
Centrosomal protein of 55 kDa (CEP55) . Q53EZ4
Centrosomal protein of 70 kDa (CEP70) . Q8NHQ1
CGG triplet repeat-binding protein 1 (CGGBP1) . Q9UFW8
Coiled-coil domain-containing protein 102B (CCDC102B) . Q68D86
Coiled-coil domain-containing protein 115 (CCDC115) . Q96NT0
Coiled-coil domain-containing protein 152 (CCDC152) . Q4G0S7
Coiled-coil domain-containing protein 184 (CCDC184) . Q52MB2
CUE domain-containing protein 1 (CUEDC1) . Q9NWM3
Disabled homolog 1 (DAB1) . O75553
Ectodysplasin-A receptor-associated adapter protein (EDARADD) . Q8WWZ3
EMILIN-3 (EMILIN3) . Q9NT22
Galectin-2 (LGALS2) . P05162
Galectin-9B (LGALS9B) . Q3B8N2
Germinal center-associated signaling and motility-like protein (GCSAML) . Q5JQS6
GRAM domain-containing protein 4 (GRAMD4) . Q6IC98
Growth arrest-specific protein 7 (GAS7) . O60861
Heat shock factor 2-binding protein (HSF2BP) . O75031
HIG1 domain family member 1C (HIGD1C) . A8MV81
Huntingtin-interacting protein M (H2AP) . O75409
KATNB1-like protein 1 (KATNBL1) . Q9H079
Kelch-like protein 12 (KLHL12) . Q53G59
Leucine-rich repeat-containing protein 73 (LRRC73) . Q5JTD7
Leukocyte receptor cluster member 1 (LENG1) . Q96BZ8
M-phase-specific PLK1-interacting protein (MPLKIP) . Q8TAP9
Melanoma-associated antigen 11 (MAGEA11) . P43364
Melanoma-associated antigen 12 (MAGEA12) . P43365
Melanoma-associated antigen 2 (MAGEA2; MAGEA2B) . P43356
Mirror-image polydactyly gene 1 protein (MIPOL1) . Q8TD10
MIT domain-containing protein 1 (MITD1) . Q8WV92
MORN repeat-containing protein 3 (MORN3) . Q6PF18
Myeloid differentiation primary response protein MyD88 (MYD88) . Q99836
Pleckstrin homology domain-containing family B member 2 (PLEKHB2) . Q96CS7
Pleckstrin homology domain-containing family J member 1 (PLEKHJ1) . Q9NW61
Protein phosphatase 1 regulatory subunit 27 (PPP1R27) . Q86WC6
Protein RD3 (RD3) . Q7Z3Z2
RAS protein activator like-3 (RASAL3) . Q86YV0
Ras/Rap GTPase-activating protein SynGAP (SYNGAP1) . Q96PV0
Rhombotin-1 (LMO1) . P25800
RNA-binding protein 20 (RBM20) . Q5T481
RNA-binding protein with multiple splicing (RBPMS) . Q93062
Saitohin (STH) . Q8IWL8
Spermatogenesis-associated protein 32 (SPATA32) . Q96LK8
Spindlin interactor and repressor of chromatin-binding protein (SPINDOC) . Q9BUA3
Tax1-binding protein 1 (TAX1BP1) . Q86VP1
TNFAIP3-interacting protein 3 (TNIP3) . Q96KP6
Transmembrane protein 239 (TMEM239) . Q8WW34
Uncharacterized protein C1orf50 (C1orf50) . Q9BV19
Uncharacterized protein CCDC197 (CCDC197) . Q8NCU1
Zinc finger CCHC domain-containing protein 17 (ZCCHC17) . Q9NP64

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.