Details of the Target
General Information of Target
| Target ID | LDTP01381 | |||||
|---|---|---|---|---|---|---|
| Target Name | Annexin A9 (ANXA9) | |||||
| Gene Name | ANXA9 | |||||
| Gene ID | 8416 | |||||
| Synonyms |
ANX31; Annexin A9; Annexin XXXI; Annexin-31; Annexin-9; Pemphaxin |
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| 3D Structure | ||||||
| Sequence |
MSVTGGKMAPSLTQEILSHLGLASKTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVD
RSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALSGNLERIVMALLQPTAQFDAQ ELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLL ALAKGGRDSYSGIIDYNLAEQDVQALQRAEGPSREETWVPVFTQRNPEHLIRVFDQYQRS TGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISR CETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALLALCRAEDM |
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| Target Bioclass |
Other
|
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| Family |
Annexin family
|
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| Function | Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C301(1.57); C151(2.61) | LDD3312 | [1] | |
|
Curcusone 37 Probe Info |
 |
3.02 | LDD0188 | [2] | |
|
NAIA_5 Probe Info |
 |
N.A. | LDD2225 | [3] | |
|
TFBX Probe Info |
 |
N.A. | LDD0148 | [4] | |
Competitor(s) Related to This Target
| Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
|---|---|---|---|---|---|
| LDCM0632 | CL-Sc | Hep-G2 | C301(20.00); C151(1.01) | LDD2227 | [3] |
| LDCM0033 | Curcusone1d | MCF-7 | 3.02 | LDD0188 | [2] |
| LDCM0022 | KB02 | ABC-1 | C301(1.99) | LDD2262 | [1] |
| LDCM0023 | KB03 | ABC-1 | C301(3.42) | LDD2679 | [1] |
| LDCM0024 | KB05 | HMCB | C301(1.57); C151(2.61) | LDD3312 | [1] |
The Interaction Atlas With This Target
References