Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name AF-1  Probe Info 
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
LFQ
Competitor Name Afatinib  Competitor Info 
In Vivo Experiment Model Model Type Living cell
Derived Tissue Skin
Disease Model Skin squamous cell carcinoma [ICD-11:2C31]
Model Name Human skin squamous cell carcinoma cells (A431)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02796  Nucleoside diphosphate kinase A (NME1) 2.7
 LDTP03764  Myosin-9 (MYH9) 2.3
 LDTP03662  Long-chain-fatty-acid--CoA ligase 1 (ACSL1) 2.2
 LDTP01785  Epidermal growth factor receptor (EGFR) 1.9

References

1 Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem. 2022 Dec 16;23(24):e202200389. doi: 10.1002/cbic.202200389. Epub 2022 Nov 22.