Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name Probe 8  Probe Info 
Probe concentration 500 nM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Compound 4  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Colon
Disease Model Colon adenocarcinoma [ICD-11:2B90]
Model Name Human colon adenocarcinoma cells (SW480)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03540  Heme oxygenase 2 (HMOX2) 2.7
 LDTP04134  Retinaldehyde dehydrogenase 3 (ALDH1A3) 1.9
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 1.8
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14217  Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) 3.1

References

1 Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2. ChemMedChem. 2017 Jun 21;12(12):917-924. doi: 10.1002/cmdc.201700028. Epub 2017 Apr 26.