General Information of Experiment

Probe Name HM-1  Probe Info 
Probe concentration 5 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name HM30181  Competitor Info 
Competitor Concentration 25 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Liver
Disease Model Hepatoblastoma [ICD-11:DB91]
Model Name Human hepatoblastoma cells (Hep-G2)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12469  Nucleolar RNA helicase 2 (DDX21) 1.9
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 1.7
 LDTP12538  Ras-related protein Rab-6B (RAB6B) 1.6
 LDTP01033  UDP-glucose 6-dehydrogenase (UGDH) 1.6
 LDTP02924  Probable ATP-dependent RNA helicase DDX5 (DDX5) 1.5

References

1 Affinity-Based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors. ACS Chem Biol. 2019 Dec 20;14(12):2546-2552. doi: 10.1021/acschembio.9b00784. Epub 2019 Nov 26.