Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name DR-1  Probe Info 
Probe concentration 1 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name DR  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Lymph node
Disease Model Lung large cell carcinoma [ICD-11:2C25]
Model Name Human lung large cell carcinoma cells (NCI-H1299)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02198  Cathepsin D (CTSD) 3.3
 LDTP03145  Catechol O-methyltransferase (COMT) 2.2
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP07236  Protein GPR107 (GPR107) 2.0

References

1 Quantitative Proteomics Reveals Cellular Off-Targets of a DDR1 Inhibitor. ACS Med Chem Lett. 2020 Feb 5;11(4):535-540. doi: 10.1021/acsmedchemlett.9b00658. eCollection 2020 Apr 9.