Details of the Target

General Information of Target

Target ID LDTP20198
Target Name Small integral membrane protein 10-like protein 1 (SMIM10L1)
Gene Name SMIM10L1
Gene ID 100129361
Synonyms
Small integral membrane protein 10-like protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMT
GHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQ
EINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKH
LKKKLKRMI
Target Bioclass
Other
Uniprot ID
P0DMW3
Ensemble ID
ENST00000622602.2
HGNC ID
HGNC:49847

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
DBIA
 Probe Info  		C28(0.98)  LDD1508  [2]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [3]
TFBX
 Probe Info  		N.A.  LDD0027  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HEK-293T C28(0.98)  LDD1508  [2]
 LDCM0259  AC14 HEK-293T C28(0.95)  LDD1512  [2]
 LDCM0277  AC18 HEK-293T C28(1.05)  LDD1516  [2]
 LDCM0279  AC2 HEK-293T C28(1.04)  LDD1518  [2]
 LDCM0282  AC22 HEK-293T C28(1.03)  LDD1521  [2]
 LDCM0286  AC26 HEK-293T C28(1.03)  LDD1525  [2]
 LDCM0291  AC30 HEK-293T C28(0.96)  LDD1530  [2]
 LDCM0295  AC34 HEK-293T C28(1.01)  LDD1534  [2]
 LDCM0299  AC38 HEK-293T C28(0.92)  LDD1538  [2]
 LDCM0304  AC42 HEK-293T C28(0.87)  LDD1543  [2]
 LDCM0308  AC46 HEK-293T C28(0.97)  LDD1547  [2]
 LDCM0313  AC50 HEK-293T C28(0.98)  LDD1552  [2]
 LDCM0317  AC54 HEK-293T C28(1.04)  LDD1556  [2]
 LDCM0321  AC58 HEK-293T C28(1.07)  LDD1560  [2]
 LDCM0323  AC6 HEK-293T C28(1.11)  LDD1562  [2]
 LDCM0326  AC62 HEK-293T C28(1.05)  LDD1565  [2]
 LDCM0367  CL1 HEK-293T C28(1.02)  LDD1571  [2]
 LDCM0368  CL10 HEK-293T C28(1.15)  LDD1572  [2]
 LDCM0370  CL101 HEK-293T C28(1.05)  LDD1574  [2]
 LDCM0374  CL105 HEK-293T C28(1.06)  LDD1578  [2]
 LDCM0378  CL109 HEK-293T C28(1.06)  LDD1582  [2]
 LDCM0383  CL113 HEK-293T C28(1.06)  LDD1587  [2]
 LDCM0387  CL117 HEK-293T C28(0.97)  LDD1591  [2]
 LDCM0392  CL121 HEK-293T C28(1.03)  LDD1596  [2]
 LDCM0396  CL125 HEK-293T C28(1.05)  LDD1600  [2]
 LDCM0400  CL13 HEK-293T C28(0.92)  LDD1604  [2]
 LDCM0405  CL18 HEK-293T C28(0.89)  LDD1609  [2]
 LDCM0410  CL22 HEK-293T C28(1.07)  LDD1614  [2]
 LDCM0413  CL25 HEK-293T C28(1.25)  LDD1617  [2]
 LDCM0419  CL30 HEK-293T C28(0.85)  LDD1623  [2]
 LDCM0423  CL34 HEK-293T C28(0.83)  LDD1627  [2]
 LDCM0426  CL37 HEK-293T C28(0.98)  LDD1630  [2]
 LDCM0432  CL42 HEK-293T C28(0.86)  LDD1636  [2]
 LDCM0436  CL46 HEK-293T C28(1.08)  LDD1640  [2]
 LDCM0439  CL49 HEK-293T C28(1.13)  LDD1643  [2]
 LDCM0445  CL54 HEK-293T C28(1.24)  LDD1648  [2]
 LDCM0449  CL58 HEK-293T C28(0.99)  LDD1652  [2]
 LDCM0451  CL6 HEK-293T C28(1.02)  LDD1654  [2]
 LDCM0453  CL61 HEK-293T C28(1.09)  LDD1656  [2]
 LDCM0458  CL66 HEK-293T C28(0.97)  LDD1661  [2]
 LDCM0463  CL70 HEK-293T C28(0.91)  LDD1666  [2]
 LDCM0466  CL73 HEK-293T C28(1.07)  LDD1669  [2]
 LDCM0471  CL78 HEK-293T C28(0.94)  LDD1674  [2]
 LDCM0476  CL82 HEK-293T C28(0.95)  LDD1679  [2]
 LDCM0479  CL85 HEK-293T C28(1.08)  LDD1682  [2]
 LDCM0485  CL90 HEK-293T C28(1.39)  LDD1688  [2]
 LDCM0489  CL94 HEK-293T C28(0.98)  LDD1692  [2]
 LDCM0492  CL97 HEK-293T C28(1.09)  LDD1695  [2]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255