Details of the Target

General Information of Target

Target ID LDTP20031
Target Name Ribosomal protein uL24-like (RPL26L1)
Gene Name RPL26L1
Gene ID 51121
Synonyms
RPL26P1; Ribosomal protein uL24-like; 60S ribosomal protein L26-like 1; Large ribosomal subunit protein uL24-like 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAMSLLQDWCRSLDVDAHRALLVTGIPEGLEQADVEAVLQPTLLPLGTFRLRHMKALMNE
KAQAALVEFVEDVNHAAIPREIPGKDGVWRVLWKDRAQDTRVLRQMRRLLLDDGPTQAAE
AGTPGEAPTPPASETQAQDSGEVTGQAGSLLGAARNPRRGRRGRRNRTRRNRLTQKGKKR
SRGGRPSAPARSEAEDSSDESLGIVIEEIDQGDLSGEEDQSALYATLQAAARELVRQWAP
CNSEGEEDGPREFLALVTVTDKSKKEEAEKEPAGAESIRLNTKEDKNGVPDLVALLAVRD
TPDEEPVDSDTSESDSQESGDQETEELDNPEFVAIVAYTDPSDPWAREEMLKIASVIESL
GWSDEKDKRDPLRQVLSVMSKDTNGTRVKVEEAGREVDAVVLRKAGDDGDLRECISTLAQ
PDLPPQAKKAGRGLFGGWSEHREDEGGLLELVALLAAQDMAEVMKEEKENAWEGGKYKYP
KGKLGEVLALLAARENMGSNEGSEEASDEQSEEESEDTESEASEPEDRASRKPRAKRART
APRGLTPAGAPPTASGARKTRAGGRGRGRGVTPEKKAGSRGSAQDDAAGSRKKKGSAGAG
AHARAGEAKGQAPTGSKAARGKKARRGRRLPPKCR
Target Bioclass
Other
Family
Universal ribosomal protein uL24 family
Uniprot ID
Q9UNX3
Ensemble ID
ENST00000265100.6
HGNC ID
HGNC:17050

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TH211
 Probe Info  		Y42(6.64)  LDD0260  [1]
OSF
 Probe Info  		Y74(0.00); H96(0.00)  LDD0029  [2]
SF
 Probe Info  		Y81(0.00); K103(0.00); Y78(0.00); Y74(0.00)  LDD0028  [2]
Acrolein
 Probe Info  		H96(0.00); H100(0.00)  LDD0217  [3]
Crotonaldehyde
 Probe Info  		H18(0.00); H24(0.00)  LDD0219  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0108  Chloroacetamide HeLa H24(0.00); H18(0.00)  LDD0222  [3]
 LDCM0107  IAA HeLa H18(0.00); H24(0.00)  LDD0221  [3]
 LDCM0109  NEM HeLa H100(0.00); H18(0.00); H24(0.00)  LDD0223  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858

The Drug(s) Related To This Target

Investigative
Click To Hide/Show 3 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
(S)-3-phenyllactic Acid . DB02494
Anisomycin . DB07374
Puromycin . DB08437

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
2 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
3 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.