Details of the Target

General Information of Target

Target ID LDTP19925
Target Name Putative HERC2-like protein 3 (HERC2P3)
Gene Name HERC2P3
Synonyms
Putative HERC2-like protein 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAATSGTDEPVSGELVSVAHALSLPAESYGNDPDIEMAWAMRAMQHAEVYYKLISSVDPQ
FLKLTKVDDQIYSEFRKNFETLRIDVLDPEELKSESAKEKWRPFCLKFNGIVEDFNYGTL
LRLDCSQGYTEENTIFAPRIQFFAIEIARNREGYNKAVYISVQDKEGEKGVNNGGEKRAD
SGEEENTKNGGEKGADSGEEKEEGINREDKTDKGGEKGKEADKEINKSGEKAM
Target Bioclass
Enzyme
Uniprot ID
Q9BVR0
HGNC ID
HGNC:4871

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C91(1.37)  LDD2634  [1]
AHL-Pu-1
 Probe Info  		C137(18.24)  LDD0171  [2]
IA-alkyne
 Probe Info  		C252(10.14)  LDD0371  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C252(10.14)  LDD0371  [2]
 LDCM0026  4SU-RNA+native RNA DM93 C137(18.24)  LDD0171  [2]
 LDCM0022  KB02 TE-11 C91(1.37)  LDD2634  [1]
 LDCM0023  KB03 KYSE-150 C91(2.27)  LDD2851  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625