Details of the Target

General Information of Target

Target ID LDTP19702
Target Name Leucine-rich repeat-containing protein 71 (LRRC71)
Gene Name LRRC71
Gene ID 149499
Synonyms
C1orf92; Leucine-rich repeat-containing protein 71
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAMVERPRPEWASYHNCNSNSCQDLGNSVLLLLGLIICINISINIVTLLWSRFRGVLYQV
FHDTICEKEAPKSSLLRKQTQPPKKQSSPAVHLRCTMDPVMMTVSPPPAHRHRRRGSPTR
CAHCPVAWAPDTDDEKPHQYPAICSYHWDVPEDWEGFQHTQGTWVPWSQDAPESPPQTIR
FQPTVEERPLKTGIWSELGLRAYVYPVNPPPPSPEAPSHKNGGEGAVPEAEAAQYQPVPA
PTLGPAVIPEFSRHRSSGRIVYDARDMRRRLRELTREVEALSGCYPLASGSSTAEETSKN
WVYRSLTGR
Target Bioclass
Other
Uniprot ID
Q8N4P6
Ensemble ID
ENST00000337428.8
HGNC ID
HGNC:26556

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
COLO679 SNV: p.P422L .
EFO27 SNV: p.T102A .
HDQP1 SNV: p.Q5H .
KO52 SNV: p.E443D .
NALM6 SNV: p.Q210Ter .
OSRC2 SNV: p.G147S .
OVK18 SNV: p.S509P .

Probe(s) Labeling This Target

PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info  		N.A.  LDD0396  [1]

References

1 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.