Details of the Target

General Information of Target

Target ID LDTP19213
Target Name Leucine-rich repeat-containing protein 63 (LRRC63)
Gene Name LRRC63
Gene ID 220416
Synonyms
Leucine-rich repeat-containing protein 63
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEADGPAQPAQPAKPIAYVKPFRR
QPPARPESPPPAERGRRRGGSRRPGRGRGRRAGPRGDAGQRQGAEGLMAPDVHIQLDHHG
EPGHQGEPEITETAAFSLSETGPPPGTVQEGPGPDVAQPELGFQEPPAAPGPQAVDWQPV
LTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY
Target Bioclass
Other
Uniprot ID
Q05C16
Ensemble ID
ENST00000595396.3
HGNC ID
HGNC:34296

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K30(8.33)  LDD0277  [1]
YN-1
 Probe Info  		N.A.  LDD0446  [2]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.