General Information of Target

Target ID LDTP18779
Target Name Putative nuclear envelope pore membrane protein POM 121B (POM121B)
Gene Name POM121B
Synonyms
Putative nuclear envelope pore membrane protein POM 121B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAGAELGAALEQRLGALAIHTEVVEHPEVFTVEEMMPHIQHLKGAHSKNLFLKDKKKKNY
WLVTVLHDRQINLNELAKQLGVGSGNLRFADETAMLEKLKVGQGCATPLALFCDGGDVKF
VLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLTFVKMTGHDPIILNFD
Target Bioclass
Transporter and channel
Family
POM121 family
Subcellular location
Nucleus, nuclear pore complex
Function Putative component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane.
Uniprot ID
A6NF01
HGNC ID
HGNC:34004

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info 
C197(2.07)  LDD0168  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C197(2.07)  LDD0168  [1]
 LDCM0026  4SU-RNA+native RNA HEK-293T C197(2.50)  LDD0169  [1]

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625