Details of the Target
General Information of Target
| Target ID | LDTP18582 | |||||
|---|---|---|---|---|---|---|
| Target Name | Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIAL4A) | |||||
| Gene Name | PPIAL4A | |||||
| Gene ID | 653505 | |||||
| Synonyms |
COAS2; PPIAL4B; Peptidyl-prolyl cis-trans isomerase A-like 4A; PPIase A-like 4A; EC 5.2.1.8; Chromosome one-amplified sequence 2; COAS-2; Cyclophilin homolog overexpressed in liver cancer |
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| 3D Structure | ||||||
| Sequence |
MTSESTSPPVVPPLHSPKSPVWPTFPFHREGSRVWERGGVPPRDLPSPLPTKRTRTYSAT
ARASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPI PPKNQKFQAVEVVLTQLAPHTPHETWSGQVVGS |
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| Target Bioclass |
Enzyme
|
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| Family |
Cyclophilin-type PPIase family, PPIase A subfamily
|
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| Subcellular location |
Cytoplasm
|
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| Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
AZ-9 Probe Info |
 |
E120(1.12) | LDD2208 | [1] | |
|
DBIA Probe Info |
 |
C52(1.24) | LDD3311 | [2] | |
|
AHL-Pu-1 Probe Info |
 |
C52(3.10) | LDD0168 | [3] | |
|
m-APA Probe Info |
 |
N.A. | LDD2231 | [4] | |
Competitor(s) Related to This Target
References