Details of the Target

General Information of Target

Target ID LDTP18174
Target Name Zinc finger protein 594 (ZNF594)
Gene Name ZNF594
Gene ID 84622
Synonyms
KIAA1871; Zinc finger protein 594; Zinc finger protein HZF18
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPHARTETSVGTYESHSTSELEDLTEPEQRELKTKLTKLEAEIVTLRHVLAAKERRCGEL
KRKLGLTALVGLRQNLSKSWLDVQVSNTYVKQKTSAALSTMGTLICRKLGGVKKSATFRS
FEGLMGTIKSKVSGGKRAWP
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q96JF6
Ensemble ID
ENST00000399604.4
HGNC ID
HGNC:29392

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K5(10.00)  LDD0277  [1]
DBIA
 Probe Info  		C85(0.96)  LDD1510  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0237  AC12 HEK-293T C85(0.96)  LDD1510  [2]
 LDCM0280  AC20 HEK-293T C85(0.99)  LDD1519  [2]
 LDCM0288  AC28 HEK-293T C85(0.95)  LDD1527  [2]
 LDCM0297  AC36 HEK-293T C85(1.02)  LDD1536  [2]
 LDCM0301  AC4 HEK-293T C85(0.96)  LDD1540  [2]
 LDCM0306  AC44 HEK-293T C85(1.07)  LDD1545  [2]
 LDCM0315  AC52 HEK-293T C85(1.00)  LDD1554  [2]
 LDCM0324  AC60 HEK-293T C85(0.98)  LDD1563  [2]
 LDCM0408  CL20 HEK-293T C85(0.90)  LDD1612  [2]
 LDCM0421  CL32 HEK-293T C85(0.90)  LDD1625  [2]
 LDCM0434  CL44 HEK-293T C85(0.92)  LDD1638  [2]
 LDCM0447  CL56 HEK-293T C85(0.89)  LDD1650  [2]
 LDCM0460  CL68 HEK-293T C85(0.98)  LDD1663  [2]
 LDCM0473  CL8 HEK-293T C85(0.84)  LDD1676  [2]
 LDCM0474  CL80 HEK-293T C85(0.93)  LDD1677  [2]
 LDCM0487  CL92 HEK-293T C85(0.90)  LDD1690  [2]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402