Details of the Target

General Information of Target

Target ID	LDTP17420
Target Name	Suprabasin (SBSN)
Gene Name	SBSN
Gene ID	374897
Synonyms	Suprabasin
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCA FCKAIVKSGGKISLKHPGKC
Target Bioclass	Other
Subcellular location	Secreted
Uniprot ID	Q6UWP8
Ensemble ID	ENST00000452271.7
HGNC ID	HGNC:24950

Target Site Mutations in Different Cell Lines

Cell line	Mutation details	Probe for labeling this protein in this cell
L428	SNV: p.K85T	.
MEWO	SNV: p.E129Ter	.
MFE296	Insertion: p.Q421AfsTer47	.
NCIH2286	SNV: p.D95G	.
NCIH661	SNV: p.G312W	.
UACC257	SNV: p.H103R	.

Probe(s) Labeling This Target

PAL-AfBPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
VE-P Probe Info			N.A.	LDD0396	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other

Click To Hide/Show 1 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Neurocalcin-delta (NCALD)				Recoverin family	P61601

References

1	Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.