Details of the Target

General Information of Target

Target ID LDTP17221
Target Name Zinc finger protein 362 (ZNF362)
Gene Name ZNF362
Gene ID 149076
Synonyms
Zinc finger protein 362
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAP
DTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGPP
GAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQ
NGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSRSLTPSPAL
GSAGSLWIAAERSSPAGRDPTRQDAALEGSTE
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q5T0B9
Ensemble ID
ENST00000373428.5
HGNC ID
HGNC:18079

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C232(1.07)  LDD3319  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C232(0.79)  LDD1507  [3]
 LDCM0270  AC15 HEK-293T C232(0.75)  LDD1513  [3]
 LDCM0276  AC17 HEK-293T C232(0.61)  LDD1515  [3]
 LDCM0281  AC21 HEK-293T C232(1.11)  LDD1520  [3]
 LDCM0283  AC23 HEK-293T C232(0.63)  LDD1522  [3]
 LDCM0285  AC25 HEK-293T C232(0.81)  LDD1524  [3]
 LDCM0289  AC29 HEK-293T C232(1.02)  LDD1528  [3]
 LDCM0292  AC31 HEK-293T C232(0.58)  LDD1531  [3]
 LDCM0294  AC33 HEK-293T C232(1.13)  LDD1533  [3]
 LDCM0298  AC37 HEK-293T C232(1.06)  LDD1537  [3]
 LDCM0300  AC39 HEK-293T C232(0.81)  LDD1539  [3]
 LDCM0303  AC41 HEK-293T C232(0.74)  LDD1542  [3]
 LDCM0307  AC45 HEK-293T C232(1.17)  LDD1546  [3]
 LDCM0309  AC47 HEK-293T C232(0.49)  LDD1548  [3]
 LDCM0311  AC49 HEK-293T C232(0.69)  LDD1550  [3]
 LDCM0312  AC5 HEK-293T C232(1.06)  LDD1551  [3]
 LDCM0316  AC53 HEK-293T C232(0.92)  LDD1555  [3]
 LDCM0318  AC55 HEK-293T C232(0.59)  LDD1557  [3]
 LDCM0320  AC57 HEK-293T C232(0.89)  LDD1559  [3]
 LDCM0325  AC61 HEK-293T C232(1.26)  LDD1564  [3]
 LDCM0327  AC63 HEK-293T C232(0.56)  LDD1566  [3]
 LDCM0334  AC7 HEK-293T C232(0.79)  LDD1568  [3]
 LDCM0248  AKOS034007472 HEK-293T C232(1.14)  LDD1511  [3]
 LDCM0356  AKOS034007680 HEK-293T C232(0.90)  LDD1570  [3]
 LDCM0379  CL11 HEK-293T C232(0.61)  LDD1583  [3]
 LDCM0404  CL17 HEK-293T C232(0.94)  LDD1608  [3]
 LDCM0409  CL21 HEK-293T C232(1.12)  LDD1613  [3]
 LDCM0411  CL23 HEK-293T C232(0.65)  LDD1615  [3]
 LDCM0417  CL29 HEK-293T C232(0.87)  LDD1621  [3]
 LDCM0422  CL33 HEK-293T C232(0.83)  LDD1626  [3]
 LDCM0424  CL35 HEK-293T C232(0.73)  LDD1628  [3]
 LDCM0431  CL41 HEK-293T C232(0.85)  LDD1635  [3]
 LDCM0435  CL45 HEK-293T C232(1.46)  LDD1639  [3]
 LDCM0437  CL47 HEK-293T C232(0.54)  LDD1641  [3]
 LDCM0440  CL5 HEK-293T C232(0.86)  LDD1644  [3]
 LDCM0444  CL53 HEK-293T C232(0.82)  LDD1647  [3]
 LDCM0448  CL57 HEK-293T C232(0.89)  LDD1651  [3]
 LDCM0450  CL59 HEK-293T C232(0.61)  LDD1653  [3]
 LDCM0457  CL65 HEK-293T C232(0.99)  LDD1660  [3]
 LDCM0461  CL69 HEK-293T C232(1.07)  LDD1664  [3]
 LDCM0464  CL71 HEK-293T C232(0.71)  LDD1667  [3]
 LDCM0470  CL77 HEK-293T C232(0.72)  LDD1673  [3]
 LDCM0475  CL81 HEK-293T C232(0.90)  LDD1678  [3]
 LDCM0477  CL83 HEK-293T C232(0.81)  LDD1680  [3]
 LDCM0483  CL89 HEK-293T C232(0.70)  LDD1686  [3]
 LDCM0484  CL9 HEK-293T C232(1.09)  LDD1687  [3]
 LDCM0488  CL93 HEK-293T C232(0.99)  LDD1691  [3]
 LDCM0490  CL95 HEK-293T C232(0.77)  LDD1693  [3]
 LDCM0022  KB02 22RV1 C232(1.40)  LDD2243  [1]
 LDCM0023  KB03 22RV1 C232(1.57)  LDD2660  [1]
 LDCM0024  KB05 MEWO C232(1.07)  LDD3319  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402