Details of the Target

General Information of Target

Target ID LDTP17042
Target Name Zinc finger protein 846 (ZNF846)
Gene Name ZNF846
Gene ID 162993
Synonyms
Zinc finger protein 846
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALPCTLGLGMLLALPGALGSGGSAEDSVGSSSVTVVLLLLLLLLLATGLALAWRRLSRD
SGGYYHPARLGAALWGRTRRLLWASPPGRWLQARAELGSTDNDLERQEDEQDTDYDHVAD
GGLQADPGEGEQQCGEASSPEQVPVRAEEARDSDTEGDLVLGSPGPASAGGSAEALLSDL
HAFAGSAAWDDSARAAGGQGLHVTAL
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q147U1
Ensemble ID
ENST00000397902.7
HGNC ID
HGNC:27260

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
NAIA_5
 Probe Info  		C312(0.35)  LDD2228  [1]
AHL-Pu-1
 Probe Info  		C396(2.31)  LDD0170  [2]
IA-alkyne
 Probe Info  		C80(0.00); C160(0.00); C1367(0.00); C65(0.00)  LDD0161  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C396(2.31)  LDD0170  [2]
 LDCM0026  4SU-RNA+native RNA DM93 C396(2.25)  LDD0171  [2]
 LDCM0634  CY-0357 Hep-G2 C312(0.35)  LDD2228  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409

References

1 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060