Details of the Target
General Information of Target
| Target ID | LDTP16917 | |||||
|---|---|---|---|---|---|---|
| Target Name | Peptidyl-prolyl cis-trans isomerase A-like 4G (PPIAL4G) | |||||
| Gene Name | PPIAL4G | |||||
| Gene ID | 644591 | |||||
| Synonyms |
Peptidyl-prolyl cis-trans isomerase A-like 4G; PPIase A-like 4G; EC 5.2.1.8; Peptidylprolyl cis-trans isomerase A-like 4 |
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| 3D Structure | ||||||
| Sequence |
MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGF
MCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTE WLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF |
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| Target Bioclass |
Enzyme
|
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| Family |
Cyclophilin-type PPIase family, PPIase A subfamily
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| Subcellular location |
Cytoplasm
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| Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
AZ-9 Probe Info |
 |
E120(1.12) | LDD2208 | [1] | |
|
NAIA_5 Probe Info |
 |
C52(20.00) | LDD2227 | [2] | |
|
AHL-Pu-1 Probe Info |
 |
C52(3.10) | LDD0168 | [3] | |
Competitor(s) Related to This Target
References