Details of the Target

General Information of Target

Target ID LDTP16770
Target Name Stathmin domain-containing protein 1 (STMND1)
Gene Name STMND1
Gene ID 401236
Synonyms
Stathmin domain-containing protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MCSSKMPCSPSASSLCAASPPNCCHPSCCQTTCCRTTSCSHSCSVSSCCRPQCCHSVCCQ
PTCCRPSCCQTTCCRTTCCHPSCCVSSCCRPQCCHSVCFQPTCCHPSCCISSSCCPSCCE
SSCCCPCCCLRPVCGRVSCHVTCYHPTCVISTCPHPLCCASPPLPLPFPSPPVPLPFFLS
LALPSPPRPSPPLLSPVLIPSPSPSPSLPSLSPPLPSPPLPSPHFPSVNPKSMLQ
Target Bioclass
Other
Uniprot ID
H3BQB6
Ensemble ID
ENST00000536551.6
HGNC ID
HGNC:44668

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C245(0.96)  LDD1513  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0270  AC15 HEK-293T C245(0.96)  LDD1513  [1]
 LDCM0283  AC23 HEK-293T C245(1.26)  LDD1522  [1]
 LDCM0292  AC31 HEK-293T C245(1.03)  LDD1531  [1]
 LDCM0300  AC39 HEK-293T C245(1.13)  LDD1539  [1]
 LDCM0309  AC47 HEK-293T C245(1.17)  LDD1548  [1]
 LDCM0318  AC55 HEK-293T C245(1.37)  LDD1557  [1]
 LDCM0327  AC63 HEK-293T C245(0.98)  LDD1566  [1]
 LDCM0334  AC7 HEK-293T C245(1.02)  LDD1568  [1]
 LDCM0379  CL11 HEK-293T C245(1.60)  LDD1583  [1]
 LDCM0411  CL23 HEK-293T C245(1.07)  LDD1615  [1]
 LDCM0424  CL35 HEK-293T C245(1.13)  LDD1628  [1]
 LDCM0437  CL47 HEK-293T C245(1.47)  LDD1641  [1]
 LDCM0450  CL59 HEK-293T C245(1.33)  LDD1653  [1]
 LDCM0464  CL71 HEK-293T C245(1.06)  LDD1667  [1]
 LDCM0477  CL83 HEK-293T C245(1.11)  LDD1680  [1]
 LDCM0490  CL95 HEK-293T C245(1.12)  LDD1693  [1]
 LDCM0022  KB02 BRX211 C39(1.47); C245(2.47)  LDD2268  [2]
 LDCM0023  KB03 BRX211 C39(1.50); C245(2.36)  LDD2685  [2]
 LDCM0024  KB05 BRX211 C39(1.90); C245(3.06)  LDD3102  [2]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840