Details of the Target

General Information of Target

Target ID LDTP16697
Target Name Putative zinc finger protein 727 (ZNF727)
Gene Name ZNF727
Gene ID 442319
Synonyms
ZNF727P; Putative zinc finger protein 727; Zinc finger protein 727 pseudogene
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSFLTVPYKLPVSLSVGSCVIIKGTLIDSSINEPQLQVDFYTEMNEDSEIAFHLRVHLGR
RVVMNSREFGIWMLEENLHYVPFEDGKPFDLRIYVCHNEYEVKVNGEYIYAFVHRIPPSY
VKMIQVWRDVSLDSVLVNNGRR
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
A8MUV8
Ensemble ID
ENST00000456806.3
HGNC ID
HGNC:22785

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		8.69  LDD2182  [1]
HHS-465
 Probe Info  		K282(0.00); K285(0.00); Y284(0.00)  LDD2240  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0625  F8 Ramos 1.66  LDD2187  [1]
 LDCM0572  Fragment10 Ramos 2.88  LDD2189  [1]
 LDCM0573  Fragment11 Ramos 5.20  LDD2190  [1]
 LDCM0574  Fragment12 Ramos 2.46  LDD2191  [1]
 LDCM0575  Fragment13 Ramos 0.90  LDD2192  [1]
 LDCM0576  Fragment14 Ramos 2.74  LDD2193  [1]
 LDCM0579  Fragment20 Ramos 4.20  LDD2194  [1]
 LDCM0580  Fragment21 Ramos 1.02  LDD2195  [1]
 LDCM0582  Fragment23 Ramos 0.76  LDD2196  [1]
 LDCM0578  Fragment27 Ramos 0.67  LDD2197  [1]
 LDCM0586  Fragment28 Ramos 1.09  LDD2198  [1]
 LDCM0588  Fragment30 Ramos 1.06  LDD2199  [1]
 LDCM0589  Fragment31 Ramos 0.95  LDD2200  [1]
 LDCM0590  Fragment32 Ramos 3.36  LDD2201  [1]
 LDCM0468  Fragment33 Ramos 1.24  LDD2202  [1]
 LDCM0596  Fragment38 Ramos 1.14  LDD2203  [1]
 LDCM0566  Fragment4 Ramos 2.76  LDD2184  [1]
 LDCM0610  Fragment52 Ramos 1.02  LDD2204  [1]
 LDCM0614  Fragment56 Ramos 1.26  LDD2205  [1]
 LDCM0569  Fragment7 Ramos 5.43  LDD2186  [1]
 LDCM0571  Fragment9 Ramos 4.58  LDD2188  [1]
 LDCM0022  KB02 Ramos 8.69  LDD2182  [1]
 LDCM0023  KB03 Ramos 3.55  LDD2183  [1]
 LDCM0024  KB05 Ramos 9.92  LDD2185  [1]

References

1 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
2 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010