Details of the Target
General Information of Target
| Target ID | LDTP16203 | |||||
|---|---|---|---|---|---|---|
| Target Name | Rap guanine nucleotide exchange factor-like 1 (RAPGEFL1) | |||||
| Gene Name | RAPGEFL1 | |||||
| Gene ID | 51195 | |||||
| Synonyms |
Rap guanine nucleotide exchange factor-like 1; Link guanine nucleotide exchange factor II; Link GEFII |
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| 3D Structure | ||||||
| Sequence |
MEPAGPCGFCPAGEVQPARYTCPRCNAPYCSLRCYRTHGTCAENFYRDQVLGELRGCSAP
PSRLASALRRLRQQRETEDEPGEAGLSSGPAPGGLSGLWERLAPGEKAAFERLLSRGEAG RLLPPWRPWWWNRGAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAERV LGDVPGACTPVVPTRIPAIVSLSRGPVSPLVRFQLPNVLFAYAHTLALYHGGDDALLSDF CATLLGVSGALGAQQVFASAEEALQAAAHVLEAGEHPPGPLGTRGAMHEVARILLGEGPT NQKGYTLAALGDLAQTLGRARKQAVAREERDHLYRARKKCQFLLAWTNENEAALTPLALD CARAHQAHAVVAEEVAALTGELERLWGGPVPPAPRTLIEELPS |
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| Target Bioclass |
Other
|
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| Function | Probable guanine nucleotide exchange factor (GEF). | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
IPM Probe Info |
 |
C555(1.89) | LDD2229 | [1] | |
|
DBIA Probe Info |
 |
C506(5.85) | LDD3312 | [2] | |
|
AHL-Pu-1 Probe Info |
 |
C506(3.18) | LDD0171 | [3] | |
|
Acrolein Probe Info |
 |
N.A. | LDD0222 | [4] | |
Competitor(s) Related to This Target
| Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
|---|---|---|---|---|---|
| LDCM0026 | 4SU-RNA+native RNA | DM93 | C506(3.18) | LDD0171 | [3] |
| LDCM0108 | Chloroacetamide | HeLa | N.A. | LDD0222 | [4] |
| LDCM0022 | KB02 | 42-MG-BA | C506(3.06) | LDD2244 | [2] |
| LDCM0023 | KB03 | 42-MG-BA | C506(3.73) | LDD2661 | [2] |
| LDCM0024 | KB05 | HMCB | C506(5.85) | LDD3312 | [2] |
References