Details of the Target

General Information of Target

Target ID LDTP15702
Target Name Zinc finger protein 707 (ZNF707)
Gene Name ZNF707
Gene ID 286075
Synonyms
Zinc finger protein 707
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MATDELATKLSRRLQMEGEGGGETPEQPGLNGAAAAAAGAPDEAAEALGSADCELSAKLL
RRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLM
MEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLCVLARLSEI
DVSSEGVKGAKSFFEAKVQAINVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQSTFK
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q96C28
Ensemble ID
ENST00000358656.9
HGNC ID
HGNC:27815

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C97(2.13)  LDD3466  [1]
NAIA_4
 Probe Info  		N.A.  LDD2226  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0259  AC14 HEK-293T C150(1.12)  LDD1512  [3]
 LDCM0282  AC22 HEK-293T C150(1.07)  LDD1521  [3]
 LDCM0291  AC30 HEK-293T C150(1.08)  LDD1530  [3]
 LDCM0299  AC38 HEK-293T C150(1.09)  LDD1538  [3]
 LDCM0308  AC46 HEK-293T C150(1.17)  LDD1547  [3]
 LDCM0317  AC54 HEK-293T C150(1.38)  LDD1556  [3]
 LDCM0323  AC6 HEK-293T C150(1.04)  LDD1562  [3]
 LDCM0326  AC62 HEK-293T C150(1.07)  LDD1565  [3]
 LDCM0368  CL10 HEK-293T C150(0.95)  LDD1572  [3]
 LDCM0410  CL22 HEK-293T C150(1.05)  LDD1614  [3]
 LDCM0423  CL34 HEK-293T C150(1.02)  LDD1627  [3]
 LDCM0436  CL46 HEK-293T C150(0.93)  LDD1640  [3]
 LDCM0449  CL58 HEK-293T C150(1.25)  LDD1652  [3]
 LDCM0463  CL70 HEK-293T C150(1.01)  LDD1666  [3]
 LDCM0476  CL82 HEK-293T C150(1.09)  LDD1679  [3]
 LDCM0489  CL94 HEK-293T C150(1.14)  LDD1692  [3]
 LDCM0022  KB02 KYSE-180 C97(2.17)  LDD2435  [1]
 LDCM0023  KB03 KYSE-180 C97(2.06)  LDD2852  [1]
 LDCM0024  KB05 TF-1 C97(2.13)  LDD3466  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402