Details of the Target

General Information of Target

Target ID LDTP15299
Target Name Protein FAM228A (FAM228A)
Gene Name FAM228A
Gene ID 653140
Synonyms
C2orf84; Protein FAM228A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDTLEEVTWANGSTALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFLIF
LLWKLPSARAKIRITSSPIFITFYILVFVVALVGIARAVVSMTVSTSNAATVADKILWEI
TRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSA
EDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERISLPSRRSFYVYAGILALLNL
LQGLGSVLLCFDIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDE
TEEPDVHLPQPYAVARREGLEAAGAAGASAASYSSTQFDSAGGVAYLDDIASMPCHTGSI
NSTDSERWKAINA
Target Bioclass
Other
Family
FAM228 family
Uniprot ID
Q86W67
Ensemble ID
ENST00000295150.8
HGNC ID
HGNC:34418

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AZ-9
 Probe Info  		2.20  LDD0393  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Diamine acetyltransferase 1 (SAT1) Acetyltransferase family P21673
Glycogen [starch] synthase, muscle (GYS1) Glycosyltransferase 3 family P13807
Tensin-2 (TNS2) PTEN phosphatase protein family Q63HR2
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) Cytochrome c oxidase subunit 5B family P10606
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 76 (ZNF76) Krueppel C2H2-type zinc-finger protein family P36508
Other
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Bystin (BYSL) Bystin family Q13895
Cyclin-dependent kinase 4 inhibitor D (CDKN2D) CDKN2 cyclin-dependent kinase inhibitor family P55273
DNA mismatch repair protein Mlh1 (MLH1) DNA mismatch repair MutL/HexB family P40692
ELL-associated factor 1 (EAF1) EAF family Q96JC9
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Sperm protein associated with the nucleus on the X chromosome N3 (SPANXN3) SPAN-X family Q5MJ09
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
Heat shock factor 2-binding protein (HSF2BP) . O75031
LIM domain transcription factor LMO4 (LMO4) . P61968

References

1 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.