Details of the Target

General Information of Target

Target ID	LDTP14817
Target Name	Zinc finger protein 543 (ZNF543)
Gene Name	ZNF543
Gene ID	125919
Synonyms	Zinc finger protein 543
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MDLSLLWVLLPLVTMAWGQYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVR SIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYF ESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVER DRQWKFIMCRMTEYDCEFANV
Target Bioclass	Transcription factor
Family	Krueppel C2H2-type zinc-finger protein family
Subcellular location	Nucleus
Function	May be involved in transcriptional regulation.
Uniprot ID	Q08ER8
Ensemble ID	ENST00000321545.5
HGNC ID	HGNC:25281

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
AHL-Pu-1 Probe Info			C453(2.31)	LDD0170	[1]

Competitor(s) Related to This Target

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0025	4SU-RNA	DM93	C453(2.31)	LDD0170	[1]
LDCM0026	4SU-RNA+native RNA	DM93	C453(2.25)	LDD0171	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other

Click To Hide/Show 3 Protein(s) Interacting with This Target

Protein name	Family	Uniprot ID
Keratin-associated protein 10-6 (KRTAP10-6)	KRTAP type 10 family	P60371
Keratin-associated protein 10-7 (KRTAP10-7)	KRTAP type 10 family	P60409
Colorectal mutant cancer protein (MCC)	MCC family	P23508

References

1	Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z. Mass spectrometry data entry: PXD044625