Details of the Target

General Information of Target

Target ID LDTP10134
Target Name Small ribosomal subunit protein mS37 (CHCHD1)
Gene Name CHCHD1
Gene ID 118487
Synonyms
C10orf34; MRPS37; Small ribosomal subunit protein mS37; 28S ribosomal protein S37, mitochondrial; MRP-S37; Coiled-coil-helix-coiled-coil-helix domain-containing protein 1; Nuclear protein C2360
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSRGTMPQPEAWPGASCAETPAREAAATARDGGKAAASGQPRPEMQCPAEHEEDMYRAAD
EIEKEKELLIHERGASEPRLSVAPEMDIMDYCKKEWRGNTQKATCMKMGYEEVSQKFTSI
RRVRGDNYCALRATLFQAMSQAVGLPPWLQDPELMLLPEKLISKYNWIKQWKLGLKFDGK
NEDLVDKIKESLTLLRKKWAGLAEMRTAEARQIACDELFTNEAEEYSLYEAVKFLMLNRA
IELYNDKEKGKEVPFFSVLLFARDTSNDPGQLLRNHLNQVGHTGGLEQVEMFLLAYAVRH
TIQVYRLSKYNTEEFITVYPTDPPKDWPVVTLIAEDDRHYNIPVRVCEETSL
Target Bioclass
Other
Family
Mitochondrion-specific ribosomal protein mS37 family
Subcellular location
Mitochondrion
Uniprot ID
Q96BP2
Ensemble ID
ENST00000372833.6
HGNC ID
HGNC:23518

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C76(5.70)  LDD0170  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [2]
NAIA_5
 Probe Info  		C76(0.00); C66(0.00)  LDD2223  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C76(5.70)  LDD0170  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
LRP chaperone MESD (MESD) MESD family Q14696
Syntenin-2 (SDCBP2) . Q9H190

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264