General Information of Target

Target ID LDTP04198
Target Name Serpin B10 (SERPINB10)
Gene Name SERPINB10
Gene ID 5273
Synonyms
PI10; Serpin B10; Bomapin; Peptidase inhibitor 10; PI-10
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF
NRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTY
AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR
MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ
LYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSY
DLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEID
IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP
Target Bioclass
Other
Family
Serpin family, Ov-serpin subfamily
Subcellular location
Nucleus
Function
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.
Uniprot ID
P48595
Ensemble ID
ENST00000238508.8
HGNC ID
HGNC:8942

Probe(s) Labeling This Target

PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info 
N.A.  LDD0396  [1]

References

1 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.