Details of the Target

General Information of Target

Target ID	LDTP03587
Target Name	Homeobox protein Hox-C13 (HOXC13)
Gene Name	HOXC13
Gene ID	3229
Synonyms	HOX3G; Homeobox protein Hox-C13; Homeobox protein Hox-3G
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGL GSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLG YGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFAS SYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLW KSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLS ERQVTIWFQNRRVKEKKVVSKSKAPHLHST
Target Bioclass	Transcription factor
Family	Abd-B homeobox family
Subcellular location	Nucleus
Function	Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes.
Uniprot ID	P31276
Ensemble ID	ENST00000243056.5
HGNC ID	HGNC:5125

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
C-Sul Probe Info			7.21	LDD0066	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor

Click To Hide/Show 2 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
ETS-related transcription factor Elf-1 (ELF1)				ETS family	P32519
Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1)				.	O95644

References

1	Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells. Anal Chem. 2022 Mar 15;94(10):4366-4372. doi: 10.1021/acs.analchem.1c05129. Epub 2022 Mar 4.