Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name IPM  Probe Info 
Probe concentration 100 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
Isotope tag
Experiment Method
ISO-TOP ABPP
Competitor Name EN6  Competitor Info 
Competitor Concentration 50 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cell lysate (HEK293-A)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP03859  V-type proton ATPase catalytic subunit A (ATP6V1A) C277 6.3
 LDTP01165  NADH dehydrogenase iron-sulfur protein 7, mitochondrial (NDUFS7) C194 4.6

References

1 Covalent targeting of the vacuolar H(+)-ATPase activates autophagy via mTORC1 inhibition. Nat Chem Biol. 2019 Aug;15(8):776-785. doi: 10.1038/s41589-019-0308-4. Epub 2019 Jul 8.