Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name 8ef  Probe Info 
Probe concentration 1 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
TMT
Competitor Name Amine 8  Competitor Info 
Competitor Concentration 50 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Acute myeloid leukemia [ICD-11:2A60]
Model Name Human acute myeloid leukemia cells (HL-60)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14109  FACT complex subunit SPT16 (SUPT16H) 3.6
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP19380  Zinc finger MYM-type protein 1 (ZMYM1) 2.7
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01074  Bromodomain-containing protein 4 (BRD4) 7.9
 LDTP06304  Bromodomain-containing protein 3 (BRD3) 6.7
 LDTP03322  Bromodomain-containing protein 2 (BRD2) 6.1

References

1 One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics. Chemistry. 2021 Dec 20;27(71):17880-17888. doi: 10.1002/chem.202102036. Epub 2021 Sep 14.