Details of the Target

General Information of Target

Target ID LDTP20000
Target Name Putative uncharacterized protein C19orf73 (C19orf73)
Gene Name C19orf73
Gene ID 55150
Synonyms
Putative uncharacterized protein C19orf73
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MPPAQGYEFAAAKGPRDELGPSFPMASPPGLELKTLSNGPQAPRRSAPLGPVAPTREGVE
NACFSSEEHETHFQNPGNTRLGSSPSPPGGVSSLPRSQRDDLSLHSEEGPALEPVSRPVD
YGFVSALVFLVSGILLVVTAYAIPREARVNPDTVTAREMERLEMYYARLGSHLDRCIIAG
LGLLTVGGMLLSVLLMVSLCKGELYRRRTFVPGKGSRKTYGSINLRMRQLNGDGGQALVE
NEVVQVSETSHTLQRS
Target Bioclass
Other
Uniprot ID
Q9NVV2
Ensemble ID
ENST00000408991.4
HGNC ID
HGNC:25534

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
BTD
 Probe Info  		C122(1.34)  LDD2090  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C122(1.17)  LDD2117  [1]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C122(1.34)  LDD2090  [1]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C122(0.87)  LDD2092  [1]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C122(1.30)  LDD2098  [1]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C122(1.03)  LDD2107  [1]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C122(0.90)  LDD2108  [1]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C122(0.55)  LDD2126  [1]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C122(0.92)  LDD2137  [1]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C122(0.64)  LDD2140  [1]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C122(1.02)  LDD2141  [1]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C122(1.39)  LDD2143  [1]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C122(1.88)  LDD2153  [1]

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761