Details of the Target

General Information of Target

Target ID LDTP19979
Target Name Putative translationally-controlled tumor protein-like protein TPT1P8 (TPT1P8)
Gene Name TPT1P8
Synonyms
Putative translationally-controlled tumor protein-like protein TPT1P8; Putative apoptosis inhibitor FKSG2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGP
VPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPC
LPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSF
ASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRP
PEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKES
VRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFL
EPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPG
TPHLLSKTPPGALLGAPPPLVPAPRPSSPPRGPGPARADR
Target Bioclass
Other
Family
TCTP family
Uniprot ID
Q9HAU6
HGNC ID
HGNC:24088

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-475
 Probe Info  		Y91(0.84)  LDD0264  [1]
NHS
 Probe Info  		N.A.  LDD0010  [2]
HHS-465
 Probe Info  		N.A.  LDD2240  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0116  HHS-0101 DM93 Y91(0.84)  LDD0264  [1]
 LDCM0117  HHS-0201 DM93 Y91(0.64)  LDD0265  [1]
 LDCM0118  HHS-0301 DM93 Y91(0.88)  LDD0266  [1]
 LDCM0119  HHS-0401 DM93 Y91(0.65)  LDD0267  [1]
 LDCM0120  HHS-0701 DM93 Y91(0.61)  LDD0268  [1]

References

1 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
2 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
3 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010