Details of the Target

General Information of Target

Target ID LDTP19856
Target Name PiggyBac transposable element-derived protein 4 (PGBD4)
Gene Name PGBD4
Gene ID 161779
Synonyms
PiggyBac transposable element-derived protein 4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKFGCLSFRQPYAGFVLNGIKTVETRWRPLLSSQRNCTIAVHIAHRDWEGDACRELLVER
LGMTPAQIQALLRKGEKFGRGVIAGLVDIGETLQCPEDLTPDEVVELENQAALTNLKQKY
LTVISNPRWLLEPIPRKGGKDVFQVDIPEHLIPLGHEV
Target Bioclass
Other
Uniprot ID
Q96DM1
Ensemble ID
ENST00000397766.4
HGNC ID
HGNC:19401

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K50(6.25)  LDD0277  [1]
DBIA
 Probe Info  		C379(2.17)  LDD3321  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A101D C379(1.87); C510(1.90)  LDD2250  [2]
 LDCM0023  KB03 A101D C379(1.59); C510(2.18)  LDD2667  [2]
 LDCM0024  KB05 SH4 C379(2.17)  LDD3321  [2]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840