General Information of Target

Target ID LDTP19848
Target Name Uncharacterized protein KIAA1143 (KIAA1143)
Gene Name KIAA1143
Gene ID 57456
Synonyms
Uncharacterized protein KIAA1143
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MSEQEAQAPGGRGLPPDMLAEQVELWWSQQPRRSALCFVVAVGLVAGCGAGGVALLSTTS
SRSGEWRLATGTVLCLLALLVLVKQLMSSAVQDMNCIRQAHHVALLRSGGGADALVVLLS
GLVLLVTGLTLAGLAAAPAPARPLAAMLSVGIALAALGSLLLLGLLLYQVGVSGHCPSIC
MATPSTHSGHGGHGSIFSISGQLSAGRRHETTSSIASLI
Target Bioclass
Other
Uniprot ID
Q96AT1
Ensemble ID
ENST00000296121.6
HGNC ID
HGNC:29198

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-475
 Probe Info 
Y109(0.51); Y9(7.71)  LDD0264  [1]
ATP probe
 Probe Info 
K117(0.00); K118(0.00)  LDD0199  [2]
m-APA
 Probe Info 
N.A.  LDD2231  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0116  HHS-0101 DM93 Y109(0.51); Y9(7.71)  LDD0264  [1]
 LDCM0117  HHS-0201 DM93 Y109(0.33); Y9(1.09)  LDD0265  [1]
 LDCM0118  HHS-0301 DM93 Y9(0.38); Y109(0.72)  LDD0266  [1]
 LDCM0119  HHS-0401 DM93 Y9(1.25); Y109(5.95)  LDD0267  [1]
 LDCM0120  HHS-0701 DM93 Y9(0.83); Y109(0.99)  LDD0268  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Centrosomal protein of 76 kDa (CEP76) CEP76 family Q8TAP6

References

1 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
2 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
3 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377