Details of the Target

General Information of Target

Target ID LDTP19832
Target Name BTB/POZ domain-containing protein KCTD4 (KCTD4)
Gene Name KCTD4
Gene ID 386618
Synonyms
BTB/POZ domain-containing protein KCTD4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLGLLVALLALGLAVFALLDVWYLVRLPCAVLRARLLQPRVRDLLAEQRFPGRVLPSDLD
LLLHMNNARYLREADFARVAHLTRCGVLGALRELRAHTVLAASCARHRRSLRLLEPFEVR
TRLLGWDDRAFYLEARFVSLRDGFVCALLRFRQHLLGTSPERVVQHLCQRRVEPPELPAD
LQHWISYNEASSQLLRMESGLSDVTKDQ
Target Bioclass
Other
Uniprot ID
Q8WVF5
Ensemble ID
ENST00000379108.2
HGNC ID
HGNC:23227

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C244(2.22)  LDD3442  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 HuH-1 C244(0.50)  LDD2374  [1]
 LDCM0023  KB03 HuH-1 C244(2.01)  LDD2791  [1]
 LDCM0024  KB05 SNU-423 C244(2.22)  LDD3442  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840