Details of the Target

General Information of Target

Target ID LDTP19826
Target Name Putative inactive carbonic anhydrase 5B-like protein (CA5BP1)
Gene Name CA5BP1
Synonyms
CA5B; CA5BL; Putative inactive carbonic anhydrase 5B-like protein; CA-VB-like protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSEQQMDLKDLMPTKRKYMWKTAEDRRMSDLTCVLEWLERRQGKKKQAPEKQKPKVVTVL
KRNKKKEEKKGKGLMTARGGNRRDTETSQQALGKRFRKDAASYRSLYGVEQKGKHLSMVP
GSYIKDGPKKSDTDIKDAVDPESTQRPNPFRRQSIVLDPMLQEGTFNSQRATFIRDWSNK
MPDMAYERKLKSLMEKSTEPKMETMRMLKPEEVLSCRYLRLSKENIRTLLKLCKDAGMNV
DIHPHMVEEDIDAKKVFTGIPSMAL
Target Bioclass
Enzyme
Family
Alpha-carbonic anhydrase family
Uniprot ID
Q8WTZ4
HGNC ID
HGNC:29544

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C149(1.63)  LDD3331  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 42-MG-BA C149(0.85)  LDD2244  [1]
 LDCM0023  KB03 42-MG-BA C149(1.04)  LDD2661  [1]
 LDCM0024  KB05 MKN-1 C149(1.63)  LDD3331  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840