Details of the Target

General Information of Target

Target ID LDTP19793
Target Name Tetratricopeptide repeat protein 16 (TTC16)
Gene Name TTC16
Gene ID 158248
Synonyms
Tetratricopeptide repeat protein 16; TPR repeat protein 16
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MCLRSHFKVAFTQRKVELSKELRRSRSSRNGGLPLQEQPMGQKWGWHRGEPGHPRMEELN
EWPQNGDHWSRKWPPPCAFTPG
Target Bioclass
Other
Uniprot ID
Q8NEE8
Ensemble ID
ENST00000373289.4
HGNC ID
HGNC:26536

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AGS SNV: p.E577A .
CCK81 SNV: p.A848T .
CHL1 SNV: p.G511A .
COLO800 SNV: p.R532H .
EOL1 SNV: p.T621K .
HCT15 Deletion: p.K591NfsTer26 .
HT3 SNV: p.A258T .
Ishikawa (Heraklio) 02 ER SNV: p.K543R .
JURKAT SNV: p.S829N .
KPL1 SNV: p.D373N .
LS180 SNV: p.A537T .
MCF7 SNV: p.D373N .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		N.A.  LDD0224  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0109  NEM HeLa N.A.  LDD0224  [1]

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.