General Information of Target

Target ID LDTP19767
Target Name Kelch repeat and BTB domain-containing protein 3 (KBTBD3)
Gene Name KBTBD3
Gene ID 143879
Synonyms
BKLHD3; Kelch repeat and BTB domain-containing protein 3; BTB and kelch domain-containing protein 3
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MELQGAQEDLGISLSSPRRNHETRPGSKAKGRSSICLQASVWMAGGKLRLRASEHLTQGH
QQELRDWNLGEDASLLFSKSPFGAGKLIQAPAHVFRQCWVQGNAWISCITKFDSKRSPEV
ASSPSYLTVPRRSPLPVFLRPSDRCVCGGCYLGKSTRRRACQSLLSDPLGVTFPTQTRP
Target Bioclass
Other
Uniprot ID
Q8NAB2
Ensemble ID
ENST00000526793.5
HGNC ID
HGNC:22934

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C350(1.11)  LDD2268  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 BRX211 C350(1.11)  LDD2268  [1]
 LDCM0023  KB03 BRX211 C350(1.14)  LDD2685  [1]
 LDCM0024  KB05 BRX211 C350(1.00)  LDD3102  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840