General Information of Target

Target ID LDTP19749
Target Name Ankyrin repeat and fibronectin type-III domain-containing protein 1 (ANKFN1)
Gene Name ANKFN1
Gene ID 162282
Synonyms
Ankyrin repeat and fibronectin type-III domain-containing protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGVSVDVHQVYKYPFEQVVASFLRKYPNPMDKNVISVKIMEEKRDESTGVIYRKRIAICQ
NVVPEILRKSLSTLVILCWKKVSILKVPNIQLEEESWLNPRERNMAIRSHCLTWTQYASM
KEESVFRESMENPNWTEFIQRGRISITGVGFLNCVLETFASTFLRQGAQKGIRIMEMLLK
EQCGAPLAE
Target Bioclass
Other
Function May play a role in neuronal function.
Uniprot ID
Q8N957
Ensemble ID
ENST00000318698.6
HGNC ID
HGNC:26766

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C638(1.76)  LDD2252  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A204 C638(1.76)  LDD2252  [1]
 LDCM0023  KB03 A204 C638(1.93)  LDD2669  [1]
 LDCM0024  KB05 A204 C638(2.21)  LDD3086  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840