Details of the Target

General Information of Target

Target ID LDTP19721
Target Name Transmembrane protein 217 (TMEM217)
Gene Name TMEM217
Gene ID 221468
Synonyms
C6orf128; Transmembrane protein 217
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGREMKKTGTPRPFRIEDPNQQPTWHDQPEMGSHYFAQAGLELLGSSNPPASASQSAGIT
GVSHCARPGEHDLNHTVFQVKDSTFLRHLESDRPEFKSCLPPHFTEPSVSLSTSEGCEDA
MG
Target Bioclass
Other
Subcellular location
Membrane
Uniprot ID
Q8N7C4
Ensemble ID
ENST00000336655.7
HGNC ID
HGNC:21238

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C62(0.12)  LDD2206  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0627  NUDT7-COV-1 HEK-293T C62(0.12)  LDD2206  [1]

References

1 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.