Details of the Target

General Information of Target

Target ID LDTP19687
Target Name Zinc finger CCHC domain-containing protein 24 (ZCCHC24)
Gene Name ZCCHC24
Gene ID 219654
Synonyms
C10orf56; Zinc finger CCHC domain-containing protein 24
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVPGEEPARELMAVLLTPRFRRLVSQNELPGPGLNGPSSRNRRDGFCRKRRTGCSGPFQA
TQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDISCLKG
VHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLGNKSSYDCCKRQKDAENEF
NETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNITVQKPFLRLSKEDVWKEQT
LLCLLQLIHLPFLDNILEPPVKTQNLQLNKEEDLVITNTCLDRELIPSLCLPEK
Target Bioclass
Other
Uniprot ID
Q8N2G6
Ensemble ID
ENST00000372336.4
HGNC ID
HGNC:26911

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C227(1.18)  LDD3332  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A-375 C227(1.16)  LDD2255  [1]
 LDCM0023  KB03 A-375 C227(1.46)  LDD2672  [1]
 LDCM0024  KB05 MKN45 C227(1.18)  LDD3332  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840