Details of the Target

General Information of Target

Target ID LDTP19671
Target Name RING finger protein 113B (RNF113B)
Gene Name RNF113B
Gene ID 140432
Synonyms
RNF161; ZNF183L1; RING finger protein 113B; Zinc finger protein 183-like 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQHPKPFCAPAAPQEGFSPQSLEGAEVLGNQPAPTCAEPPPAMGSLNLYHPPDPEKEVFP
APPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQP
YLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP
APLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR
PGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGAS
EPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKA
LDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGAT
PH
Target Bioclass
Other
Uniprot ID
Q8IZP6
Ensemble ID
ENST00000267291.7
HGNC ID
HGNC:17267

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C202(1.18)  LDD3310  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 22RV1 C202(1.21)  LDD2243  [1]
 LDCM0023  KB03 42-MG-BA C202(1.48)  LDD2661  [1]
 LDCM0024  KB05 COLO792 C202(1.18)  LDD3310  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840