Details of the Target

General Information of Target

Target ID LDTP19549
Target Name Homeobox protein DBX2 (DBX2)
Gene Name DBX2
Gene ID 440097
Synonyms
Homeobox protein DBX2; Developing brain homeobox protein 2
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAPVKISHVVSFSSQDPKYPVENLLNPDSPRRPWLGCPQDKSGQLKVELQLERAVPTGYI
DVGNCGCAFLQIDVGHSSWPLDRPFITLLPATTLMSLTDSKQGKNRSGVRMFKDVDFLAP
ASGELWDRLRLTCSRPFTRHQSFGLAFLRVCSSLDSLDDSVVGPSALLSSVLNKIREFKT
CFFSWSLKKMELEFSPLLLSINLNDLQFAADAEVSTVSNCMFISIALQSAMIIF
Target Bioclass
Transcription factor
Family
H2.0 homeobox family
Subcellular location
Nucleus
Uniprot ID
Q6ZNG2
Ensemble ID
ENST00000332700.6
HGNC ID
HGNC:33186

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C127(0.94)  LDD2183  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0625  F8 Ramos C127(0.80)  LDD2187  [1]
 LDCM0573  Fragment11 Ramos C127(9.05)  LDD2190  [1]
 LDCM0575  Fragment13 Ramos C127(0.55)  LDD2192  [1]
 LDCM0576  Fragment14 Ramos C127(0.84)  LDD2193  [1]
 LDCM0580  Fragment21 Ramos C127(1.28)  LDD2195  [1]
 LDCM0582  Fragment23 Ramos C127(1.40)  LDD2196  [1]
 LDCM0588  Fragment30 Ramos C127(0.95)  LDD2199  [1]
 LDCM0566  Fragment4 Ramos C127(0.93)  LDD2184  [1]
 LDCM0610  Fragment52 Ramos C127(0.57)  LDD2204  [1]
 LDCM0614  Fragment56 Ramos C127(0.85)  LDD2205  [1]
 LDCM0569  Fragment7 Ramos C127(0.53)  LDD2186  [1]
 LDCM0023  KB03 Ramos C127(0.94)  LDD2183  [1]
 LDCM0024  KB05 Ramos C127(0.96)  LDD2185  [1]

References

1 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578